Dr. Frick has been awarded a 5-year R01 grant by the National Institute of Mental Health.  The grant is entitled, Mechanisms underlying memory regulation of 17beta-estradiol, canonical Wnt signaling, and BDNF in male and female mice.  The goal of this project is to determine the extent to which canonical Wnt signaling and BDNF contribute to the memory enhancing effects of estradiol in female and male mice.