Publications

Literature

  1. T.N. Malla, S. Muniyappan, D. Menendez, F. Ogukwe, A.N. Dale, J.D. Clayton, D.D. Weatherall, P. Karki, S. Dangi, V. Mandella, A.A. Pacheco, E.A. Stojković, S.L. Rose, J. Orlans, S. Basu, D. de Sanctis, M. Schmidt (2025), Exploiting microseconds X-ray pulses for time-resolved serial synchrotron crystallography at ESRF-EBS ID29, IUCrJ 12, doi.org/10.1107/S2052252524010868.
  2. Z. Liu, K. Gu, M. Shelby, D. Roy, S. Muniyappan, M. Schmidt, S. R. Narayanasamy, M. Coleman, M. Frank, T. Kuhl (2024) In-situ Counter Diffusion Crystallization and Long-Term Crystal Preservation in Microfluidic Fixed Targets For Serial Crystallography, J. Appl. Cryst. 57, doi.org/10.1107/S1600576724007544.
  3. M. Schmidt (2024) Commentary: The structure of Chlamydomonas LOV1 as revealed by time-resolved serial synchrotron crystallography, IUCrJ, 11, https://doi.org/10.1107/S2052252524008327.
  4. T.N. Malla, C. Hernandez, S. Muniyappan, D. Menendez, D. Bizhga, J.H. Mendez, P. Schwander, E.A. Stojković, M. Schmidt (2024) Photoreception and signaling in bacterial phytochrome revealed by single-particle cryo-EM, Science Advances 10, eadq0653, 1-10, see also BioRxiv, doi.org/10.1101/2023.11.08.566274.
  5. G. Biener, T. N. Malla, P. Schwander, M. Schmidt (2024) KINNTREX: A Neural Network Unveils Protein Mechanism from Time Resolved X-ray Crystallography (2024) IUCrJ 11, https://doi.org/10.1107/S2052252524002392, see also bioRxiv, doi.org/10.1101/2023.10.06.561268.
  6. M. Schmidt, E. A. Stojkovic (2024) Blue and Red in the Protein World: Photoactive Yellow Protein and Phytochromes as Revealed by Time-Resolved Crystallography, Structural Dynamics 11, 014701, https://doi.org/10.1063/4.0000233.
  7. A. Cellini, M. Kumar, A. Nimmrich, J. Mutisya, A. Furrer, E. V. Beale, M. Carrillo, T. Malla, P. Maj, F. Dworkowskic, C. Bacellar, J. Standfuss, M. Schmidt, T. Weinert, J. A. Ihalainen, W. Yuan Wahlgren, S. Westenhoff (2024) Femtosecond serial crystallography resolves conformational changes which guide long-range electron transfer in a photolyase, Nature Chemistry, Jan 15 2024, DOI: 10.1038/s41557-023-01413-9.
  8. M. Schmidt (2023) Time-resolved Crystallography on Protein Photoreceptors and Enzymes, in: Integrated Structural Biology, New Developments in NMR (T. Polenova, C.M. Quinn, A.M. Gronenborn, eds.), The Royal Society of Chemistry, pages 203 – 240, doi.org/10.1039/9781837670154.
  9. T.N. Malla, K. Zielinski, L. Aldama, S. Bajt, D. Feliz, B. Hayes, M. Hunter, C. Kupitz, S. Lisova, J. Knoska, J. Martin-Garcia, V. Mariani, S. Pandey, I. Poudyal, R. G. Sierra, A. Tolstikova, O. Yefanov, C.-H. Yoon, A. Ourmazd, P. Fromme, P. Schwander1, A. Barty, H. N. Chapman, E. A. Stojkovic, A. Batyuk, S. Boutet, G. N. Phillips, Jr., L. Pollack, M. Schmidt (2023) Heterogeneity in the M. tuberculosis β-Lactamase Inhibition by Sulbactam, Nature Communications, published online on Sep 7 2023, 10.1038/s41467-023-41246-1, on bioRxiv since Dec. 6 2022; doi: https://doi.org/10.1101/2022.12.06.519319, also available on Research Square https://doi.org/10.21203/rs.3.rs-2334665/v1.
  10. M. Schmidt (2023) Practical Considerations for the Analysis of Time-Resolved X-ray Data, Structural Dynamics 10 (4), 044303, https://doi.org/10.1063/4.0000196, editor’s pick, on the cover of the July 2023 issue of Str. Dyn.
  11. C.D.M. Hutchison, J.M. Baxter, A. Fitzpatrick, G. Dorlhiac, A. Fadini, S. Perrett, K. Maghlaoui, S. Bodet Lefèvre, V. Cordon-Preciado, J. L. Ferreira, V. Chukhutsina, D. Garratt, J. Barnard, G. Galinis, F. Glencross, R.M. Morgan, S. Stockton, B. Taylor, L. Yuan, M.G. Romei, C.-Y. Lin, J.P. Marangos, M. Schmidt, V. Chatrchyan, T. Buckup, D. Morozov, J. Park, S. Park, I. Eom, M. Kim, D. Jang, H. Choi, H. Hyun, G. Park, E. Nango, R. Tanaka, S. Owada, K. Tono, T. Nakane, D.P. DePonte, S. Carbajo, M. Seaberg, A. Aquila, S. Boutet, A. Barty, S. Iwata, S.G. Boxer, G. Groenhof, J.J. van Thor (2023) Amplification of ultrafast structural motion in a photo-excited fluorescent protein, Nature Chemistry, published online, https://doi.org/10.1038/s41557-023-01275-1.
  12. M. Schmidt, E. Stojkovic (2023) News and Views: Earliest molecular events of vision revealed, Nature , 615, 802-803, https://www.nature.com/articles/d41586-023-00504-4.
  13. M. Schmidt (2023) Biological Function Investigated by Time-Resolved Structure Determination, Structural Dynamics 10, 01090, on the cover of the Jan 2023 issue of Str. Dyn. https://doi.org/10.1063/4.0000177.
  14. R. J. Jernigan, D. Logeswaran, D. Doppler, N. Nagaratnam, M. Sonker, J.-H. Yang, G. Ketawala, J. M. Martin-Garcia, M. Shelby, T. Grant, V. Mariani, A. Tolstikova, M. Sheikh, M. C. Yung, M. Coleman, S. Zahre, E. K. Kaschner, M. T. Rabbani, R. Nasari, M. A. Zacks, B. Hayes, R. Sierra, M. S. Hunter, S. Lisova, A. Batyuk, C. Kupitz, S. Boutet, D. T. Hansen, R. Kirian, M. Schmidt, R. Fromme, M. Frank, A. Ros, J. J.-L. Chen, S. Botha, P. Fromme (2023) Room Temperature Structural Studies of SARS-CoV-2 Protein NendoU with an X-ray Free Electron Laser, Structure 31, 1–14, https://doi.org/10.1016/j.str.2022.12.009.
  15. S. Westenhoff, P. Meszaros, M. Schmidt (2022) Protein motions visualized by femtosecond time resolved crystallography: The case of photosensory vs photosynthetic proteins, Current Opinion in Structural Biology 77:102481, https://doi.org/10.1016/j.sbi.2022.102481.
  16. M. Schmidt (2022) Gefilmte Proteindynamik, Physik in unserer Zeit, 53 (5), 228-235, https://doi.org/10.1002/piuz.202201646.
  17. T.N. Malla, M. Schmidt (2022) Transient state measurements on proteins by time-resolved crystallography, Current Opinion in Structural Biology 74, 102376, doi: 10.1016/j.sbi.2022.102376.
  18. D. Doppler, M.T. Rabbani, R. Letrun, J. Cruz Villarreal, D.H. Kim, S. Gandhi, A. Egatz-Gomez, M. Sonker, J. Chen, F.H.M. Koua, J. Yang, M.H. Youssef, V. Mazalova, S. Bajt, M.L. Shelby, M.A. Coleman, M.O. Wiedorn, J. Knoska, S. Schön, T. Sato, M.S. Hunter, A. Hosseinizadeh, C. Kupitz, R. Nazari, R.C. Alvarez, K. Karpos, S. Zaare, Z. Dobson, E. Discianno, S. Zhang, J.D. Zook, J. Bielecki, R. de Wijn, A.R. Round, P. Vagovic, M. Kloos, M. Vakili, G.K. Ketawala, N.E .Stander, T.L. Olson, K. Morin, J. Mondal, J. Nguyen, J.D. Meza-Aguilar, G. Codis, S. Vaiana, J.M. Martin-Garcia, V. Mariani, P. Schwander, M. Schmidt, M. Messerschmidt, A. Ourmazd, N. Zatsepin, U. Weierstall, B. Bruce, A.P. Mancuso, T. Grant, A. Barty, H.N. Chapman, M. Frank, R. Fromme, J.C.H. Spence, S. Botha, P. Fromme, R.A. Kirian, A. Ros (2022) Co-flow Injection for Serial Crystallography at X-Ray Free Electron Lasers, J. Appl. Cryst. 55 , doi.org/10.1107/S1600576721011079.
  19. M. Schmidt (2021) Macromolecular Movies, Storybooks Written by Nature, Biophysical Reviews, https://doi.org/10.1007/s12551-021-00846-1.
  20. A. Hosseinizadeh, N. Breckwoldt, R. Fung, R. Sepehr, M. Schmidt, P. Schwander, R. Santra, A. Ourmazd (2021) Single-femtosecond atomic-resolution observation of a protein traversing a conical intersection, Nature, 599, 697–701, https://doi.org/10.1038/s41586-021-04050-9 (also available on BioRxiv: https://doi.org/10.1101/2020.11.13.382218).
  21. S. Pandey, G. Calvey, A. M. Katz, T. N. Malla, F. H. M. Koua, I. Poudyal, J.-H. Yang, M. Vakili, J. Martin-Garcia, O. Yefanov, K. A. Zielinski, S. Bajt, K. Doerner, M. Frank, L. Gelesio, R. Jernigan, M. Kloos, V. Mariani, M. D. Miller, G. Nelson, J. Olmos, A. Ourmazd, A. Sadri, A. Salah, A. Tolstikova, J. Spence, P. Schwander, A. Barty, H. Chapman, P. Fromme, A. Mancuso, G. Phillips, R. Bean, L. Pollack, M. Schmidt (2021) Observation of substrate diffusion and ligand binding in enzyme crystals using high-repetition rate mix-and-inject serial crystallography, IUCrJ 8(6), 878-895, https://doi.org/10.1107/S2052252521008125 (also available on BioRxiv).
  22. A. Cellini, W.Y. Wahlgren, L. Henry, S. Pandey, S. Ghosh, L. Castillon, E. Claesson, H. Takala, J. Kuebel, A. Nimmrich, V. Kuznetsova, E. Nango, S. Iwata, S. Owada, E.A. Stojkovic ́, M. Schmidt, J.A. Ihalainen, S. Westenhoff (2021) The three-dimensional structure of Drosophila melanogaster(6–4) photolyase at room temperature, Acta Cryst. D77, 1001–1009, https://doi.org/10.1107/S205979832100583.
  23. J.-H. Yun, X. Li, J. Yue, J.-H. Park, Z. Jin, C. Li, H. Hu, Y. Shi, S. Pandey, S. Carbajo, S. Boutet, M. S. Hunter, M. Liang, R. G. Sierra, T. J. Lane, L. Zhou, U. Weierstall, N. A. Zatsepin, M. Ohki, J. R. H. Tame, S.-Y. Park, J. C. H. Spence, W. Zhang, M. Schmidt*, W. Lee*, H. Liu* (2021) Early stage dynamics of chloride ion-pumping rhodopsins revealed by femtosecond X-ray laser, Proc. Natl. Acad. Sci., https://doi.org/10.1073/pnas.2020486118, *co-corresponding.
  24. M. Carrillo, S. Pandey, J. Sanchez, M. Noda, I. Poudyal, L. Aldama, T. N. Malla, E. Claesson, W. Yuan Wahlgren, D. Feliz, V. Šrajer, M. Maj, L. Castillon, S. Iwata, E. Nango, R. Tanaka, T. Tanaka, L. Fangjia, K. Tono, S. Owada, S. Westenhoff*, E. A. Stojković*, M. Schmidt* (2021) High-resolution Crystal Structures of Transient Intermediates in the Phytochrome Photocycle, Structure, https://doi.org/10.1016/j.str.2021.03.004 (also available on BioRxiv, https://doi.org/10.1101/2020.09.16.298463), *co-corresponding.
  25. S. Ramakrishnan, J. R. Stagno, C. E. Conrad, J. Ding, P. Yu, Y. R. Bhandari, Y.-T. Lee, G. Pauly, O. Yefanov, M. O. Wiedorn, J. Knoska, D. Oberthuer, T. A. White, A. Barty, V. Mariani, C. Li, W. Brehm, W. F. Heinz, V. Magidson, S. Lockett, M. S. Hunter, S. Boutet, N. A. Zatsepin, X. Zuo, T. D. Grant, S. Pandey, M. Schmidt, J. C. H. Spence, H. N. Chapman, Y.-X. Wang (2021) Synchronous RNA conformational changes trigger ordered phase transitions in crystals, Nature Communications, https://doi.org/10.1038/s41467-021-218.
  26. C. Sanchez-Cano, R. A. Alvarez-Puebla, J. M. Abendroth, T. Beck, R. Blick, Y. Cao, F. Caruso, I. Chakraborty, H. Chapman, C. Chen, B. E. Cohen, A. L. C. Conceicao, D. P. Cormode, D. Cui, K. A. Dawson, G. Falkenberg, C. Fan, N. Feliu, M. Gao, E. Gargioni, C.-C. Glueer, F. Gruener, M. Hassan, Y. Hu, Y. Huang, S. Huber, N. Huse, Y. Kang, A. Khademhosseini, T. F. Keller, C. Koernig, N. A. Kotov, D. Koziej, X.-J. Liang, B. Liu, S. Liu, Y. Liu, Z. Liu, L. M. Liz-Marzan, X. Ma, A. Machicote, W. Maison, A. P. Mancuso, S. Megahed, B. Nickel, F. Otto, C. Palencia, S. Pascarelli, A. Pearson, O. Peñate-Medina, B. Qi, J. Raedler, J. J. Richardson, A. Rosenhahn, K. Rothkamm, M. Ruebhausen, M. K. Sanyal, R. E. Schaak, H.-P. Schlemmer, M. Schmidt, O. Schmutzler, T. Schotten, F. Schulz, A. K. Sood, K. M. Spiers, T. Staufer, D. M. Stemer, A. Stierle, X. Sun, G. Tsakanova, P. S. Weiss, H. Weller, F. Westermeier, M. Xu, H. Yan, Y. Zeng, Y. Zhao, Y. Zhao, D. Zhu, Y. Zhu, W. J. Parak (2021) X‑ray-Based Techniques to Study the Nano−Bio Interface, ACS Nano, https://doi.org/10.1021/acsnano.0c09563.
  27. T.N. Malla, S. Pandey, I. Poudyal, D. Feliz, M. Noda, G. Phillips, E. Stojkovic, M. Schmidt* (2020) Ebselen Reacts with SARS Coronavirus-2 Main Protease Crystals. Published on BioRxiv for rapid disemination of results during the Covid-19 pandemic. BioRxiv 2020.08.10.244525; doi: https://doi.org/10.1101/2020.08.10.244525
  28. E. Claesson, W. Y. Wahlgren, H. Takala, S. Pandey, L. Castillon, V. Kuznetsova, L. Henry, M. Carrillo5, M. Panman, J. Kubel, R. Nanekar, L. Isaksson, A. Nimmrich, A. Cellini, D. Morozov, M. Maj, M. Kurttila, R. Bosman, E. Nango, R. Tanaka, T. Tanaka, L. Fangjia, S. Iwata, S. Owada, G. Groenhof, E. A. Stojkovic, J. A. Ihalainen, M. Schmidt*, S. Westenhoff* (2020) The primary structural photoresponse of phytochrome proteins captured by a femtosecond X-ray laser, eLife 9, e53514, https://doi.org/10.7554/eLife.53514, also available on BioRxiv, https://doi.org/10.1101/789305, *co-corresponding
  29. I. Poudyal, M. Schmidt, P. Schwander (2020) Single-Particle Imaging by X-ray Free Electron Lasers – How Many Snapshots are Needed?, Structural Dynamics 7, 024102, https://doi.org/10.1063/1.514451.
  30. M. Schmidt (2020) Reaction Initiation in Enzyme Crystals by Diffusion of Substrate, Crystals 10, 116, doi:10.3390/cryst10020116.
  31. O. Yefanov, D. Oberthür, R. Bean, M. O. Wiedorn, J. Knoska, G. Pena, S. Awel, L. Gumprecht, M. Domaracky, I. Sarrou, P. L. Xavier, S. Bajt, V. Mariani, Y. Gevorkov, T. A. White, A. Tolstikova, P. Villanueva-Perez, C. Seuring, S. Aplin, A. D. Estillore, J. Küpper, A. Kluyev, M. Kuhn, T. Laurus, H. Graafsma, D. C. F. Monteiro, M. Trebbin, F. R. N. C. Maia, F. Cruz-Mazo, A. M. Gañán-Calvo, M. Heymann, C. Darmanin, B. Abbey, M. Schmidt, P. Fromme, K. Giewekemeyer, M. Sikorski, R. Graceffa, P. Vagovic, T. Kluyver, M. Bergemann, H. Fangohr, J. Sztuk-Dambietz, S. Hauf, N. Raab, V. Bondar, A. P. Mancuso, H. N. Chapman, A. Barty (2019) Evaluation of serial crystallographic structure determination within megahertz pulse trains, Struct. Dyn. 6, 064702, https://doi.org/10.1063/1.5124387.
  32. S. Pandey #, R. Bean#, T. Sato#, I. Poudyal, J. Bielecki, J. Cruz Villarreal, O. Yefanov, V. Mariani, T. A. White, C. Kupitz, M. Hunter, M. H. Abdellatif, S. Bajt, V. Bondar, A. Echelmeier, D. Doppler, M. Emons, M. Frank, R. Fromme, Y. Gevorkov, G. Giovanetti, M. Jiang, D. Kim, Y. Kim, H. Kirkwood, A. Klimovskaia, J. Knoska, F. H. M. Koua, R. Letrun, S. Lisova, L. Maia, V. Mazalova, D. Meza, T. Michelat, A. Ourmazd, G. Palmer, M. Ramilli, R. Schubert, P. Schwander, A. Silenzi, J. Sztuk-Dambietz, A. Tolstikova, H. N. Chapman, A. Ros, A. Barty, P. Fromme, A. P. Mancuso, M. Schmidt (2019) Time-Resolved Serial Femtosecond Crystallography at the European XFEL. Nature Methods, 17, 73–78, https://doi.org/10.1038/s41592-019-0628-z. #contributed equally.
  33. C. Gisriel, J. Coe, R. Letrun, C. Luna-Chavez, N. E. Stander, S. Lisova, O. N. Yefanov, V. Mariani, M. Kuhn, T. D. Grant, K. Dörner, T. Sato, A. Echelmeier, J. C. Villarreal, M. S. Hunter, M. O. Wiedorn, J. Knoska, V. Mazalova, S. Roy-Chowdhury, J.-H. Yang, A. Jones, R. Bean, J. Bielecki, Y. Kim, G. Mills, B. Weinhausen, J. D. Meza, N. Al-Qudami, S. Bajt, G. Brehm, S. Botha, D. Boukhelef, S. Brockhauser, B. D. Bruce, M. A. Coleman, C. Danilevski, E. Discianno, Z. Dobson, H. Fangohr, J. M. Martin-Garcia, Y. Gevorkov, S. Hauf, A. Hosseinizadeh, F. Januschek, G. K. Ketawala, C. Kupitz, L. Maia, M. Manetti, M. Messerschmidt, T. Michelat, J. Mondal, A. Ourmazd, G. Previtali, I. Sarrou, S. Schön, P. Schwander, M. L. Shelby, A. Silenzi, J. Sztuk-Dambietz, J. Szuba, M. Turcato, T. A. White, Wrona, C. Xu, M. H. Abdellatif, J. D. Zook, J. C. H. Spence, H. N. Chapman, A. Barty, R. A. Kirian, M. Frank, A. Ros, M. Schmidt, R. Fromme, A. P. Mancuso, P. Fromme, N. A. Zatsepin (2019) Membrane Protein Megahertz Crystallography at the European XFEL, Nature Communications, 10:5021, https://doi.org/10.1038/s41467-019-12955-3.
  34. J. Sanchez, M. Carrillo, S. Pandey, M. Noda, L. Aldama, D. Feliz, E. Claesson, W. Y. Wahlgren, G. C. Tracy, P. Duong, A. Nugent, A. Field, V. Šrajer, C. Kupitz, S. Iwata, E. Nango, R. Tanaka, T. Tanaka, L. Fangjia, K. Tono, S. Owada, Sebastian Westenhoff, M. Schmidt*, Emina A. Stojković* (2019) High-resolution crystal structures of a myxobacterial phytochrome at cryo and room temperatures, Structural Dynamics, 6, 054701, https://doi.org/10.1063/1.5120527. *co-corresponding
  35. M. Ali, N. Stein,Y. Mao, S. Shahid, M. Schmidt, B. Bennett, A. A. Pacheco (2019) Trapping of a putative intermediate in the cytochrome c nitrite reductase (ccNiR)-catalyzed reduction of nitrite: implications for the ccNiR reaction mechanism. Journal of the American Chemical Society, 141, 13358-13371, DOI: 10.1021/jacs.9b03036.
  36. M. Schmidt(2019) Time-Resolved Macromolecular Crystallography at Pulsed X-ray Sources, International Journal of Molecular Sciences, 20, 1401; doi:10.3390/ijms20061401.
  37. K.A. Niessen, M. Xu, D.K. George, M.C. Chen, A.R. Ferre-D’Amare, E.H. Snell, V. Cody, J. Pace, M. Schmidt, A. Markelz (2019) Protein and RNA Dynamical Fingerprinting, Nature Communications 10, 1026, DOI: 10.1038/s41467-019-08926-3.
  38. M. O. Wiedorn, D. Oberthur, R. Bean, R. Schubert, N. Werner, B. Abbey, M. Aepfelbacher, L. Adriano, A. Allahgholi, N. Al-Qudami, J. Andreasson, S. Aplin, S. Awel, K. Ayyer, S. Bajt, I. Barak, S. Bari, J. Bielecki, S. Botha, D. Boukhelef, W. Brehm, S. Brockhauser, I. Cheviakov, M. A. Coleman, F. Cruz-Mazo, C. Danilevski, C. Darmanin, R. B. Doak, M. Domaracky, K. Dorner, Y. Du, H. Fangohr, H. Fleckenstein, M. Frank, P. Fromme, A. M. Ganan-Calvo, Y. Gevorkov, K. Giewekemeyer, H. M. Ginn, H. Graafsma, R. Graceffa, D. Greiffenberg, L. Gumprecht, P. Gottlicher, J. Hajdu, S. Hauf, M. Heymann, S. Holmes, D. A. Horke, M. S. Hunter, S. Imlau, A. Kaukher, Y. Kim, A. Klyuev, J. Knoska, B. Kobe, M. Kuhn, C. Kupitz, J. Kupper, J. M. Lahey-Rudolph, T. Laurus, K. Le Cong, R. Letrun, P. L. Xavier, L. Maia, F. Maia, V. Mariani, M. Messerschmidt, M. Metz, D. Mezza, T. Michelat, G. Mills, D. C. F. Monteiro, A. Morgan, K. Muhlig, A. Munke, A. Munnich, J. Nette, K. A. Nugent, T. Nuguid, A. M. Orville, S. Pandey, G. Pena, P. Villanueva-Perez, J. Poehlsen, G. Previtali, L. Redecke, W. M. Riekehr, H. Rohde, A. Round, T. Safenreiter, I. Sarrou, T. Sato, M. Schmidt, B. Schmitt, R. Schonherr, J. Schulz, J. A. Sellberg, M. M. Seibert, C. Seuring, M. L. Shelby, R. L. Shoeman, M. Sikorski, A. Silenzi, C. A. Stan, X. Shi, S. Stern, J. Sztuk-Dambietz, J. Szuba, A. Tolstikova, M. Trebbin, U. Trunk, P. Vagovic, T. Ve, B. Weinhausen, T. A. White, K. Wrona, C. Xu, O. Yefanov, N. Zatsepin, J. Zhang, M. Perbandt, A. P. Mancuso, C. Betzel, H. Chapman, A. Barty (2018) Megahertz serial crystallography, Nature Communications 9 (1), 4025, DOI: 10.1038/s41467-018-06156-7.
  39. C. Kupitz, M. Schmidt (2018) Towards Molecular Movies of Enzymes. In: X-ray Free Electron Lasers, A Revolution in Structural Biology (S. Boutet, P. Fromme, M. Hunter eds.), Springer, Cham (Switzerland), ISBN 978-3-030-00550-4, p. 357-376.
  40. N. C. Woitowich, A. S. Halavati, P. Waltz, C. Kupitz, J. Valera, G. Tracy, K.D. Gallagher, E. Claesson, T. Nakana, S. Pandey, G. Nelson, R. Tanaka, E. Nango, E. Mizohata, S. Owada, K. Tono, Y. Joti, A.C. Nugent, H. Patel, A. Mapara, J. Hopkins, P. Duong, D. Bizhga, S.E. Kovaleva, R. St. Peter, C.N. Hernandez, W.B. Ozarowski, S. Roy-Chowdhuri, J-H Yang, P. Edlund, H. Takala, J. Ihalainen, J. Brayshaw, T. Norwood, I. Poudyal, P. Fromme, J.C.H. Spence, K. Moffat, S. Westenhoff, M. Schmidt*, E. Stojkovic* (2018) Structural Basis for Light Control of Cell Development as Revealed by Crystal Structures of a Myxobacterial Phytochrome, IUCrJ 5 , https://doi.org/10.1107/S2052252518010631, *co-corresponding.
  41. J. Olmos, S. Pandey, J. Martin-Garcia, G. Calvey, A. Katz, J. Knoska, C. Kupitz, M. S. Hunter, M. Liang, D. Oberthuer, O. Yefanov, M. Wiedorn, M. Heyman, M. Holl, K. Pande, A. Barty, M. D. Miller, S. Stern, S. Roy-Chowdhury, J. Coe, N. Nagaratnam, J. Zook, J. Verburgt, T. Norwood, I. Poudyal, D. Xu, J. Koglin, M. H. Seaberg, Y. Zhao, S. Bajt, T. Grant, V. Mariani, G. Nelson, G. Subramanian, E. Bae, R. Fromme, R. Fung, P. Schwander, M. Frank, T. A. White, U. Weierstall, N. Zatsepin, J. Spence, P. Fromme, H. N. Chapman, L. Pollacket, L. Trembley, A. Ourmazd, G. Phillips, M. Schmidt (2018) Authentic Enzyme Intermediates Captured “on-the-fly” by Mix-and-Inject Serial Crystallography, BMC-Biology 16:59 , (see also commentary by Allen Orville).
  42. A. Hosseinizadeh, G. Mashayekhi, J. Copperman, P. Schwander, A. Dashti, R. Fung, M. Schmidt, C. Yoon, A. Aquilla, A. Ourmazd (2017) Conformational Landscape of a Virus by Single-particle X-ray Scattering, Nature Methods, doi:10.1038/nmeth.4395.
  43. V. Srajer, M. Schmidt (2017) Watching Proteins Function with Time-resolved X-ray Crystallography, J. Phys. D. Appl. Phys. 50 373001.
  44. M. Schmidt (2017) Time-resolved crystallography at Modern X-ray sources. In: Methods in Molecular Biology, Protein Crystallography (A. Wlodaver, S. Dauter, M. Jaskolski, eds.), Humana-Press, Springer, pp. 273-295,.
  45. M. Schmidt (2017) A short history of structure based research on the photocycle of photoactive yellow protein , Structural Dynamics, 4, 032201.
  46. C. Kupitz, J. L. Olmos Jr., M. Holl, L. Tremblay, K. Pande, S. Pandey, D. Oberthür, M. Hunter, M. Liang, A. Aquila, J. Tenboer, G. Calvey, A. Katz, Y. Chen, M.O. Wiedorn, J. Knoska, A. Meents, V. Mariani, T. Norwood, I. Poudyal, T. Grant, M. D. Miller, W. Xu, A. Tolstikova, A. Morgan, M. Metz, J. Martin-Gracia, J.D. Zook, S. Roy-Chowdhury, J. Coe, N. Nagaratnam, D. Meza, R. Fromme, S. Basu, M. Frank, T. White, A. Barty, S. Bajt, O. Yefanov, H.N. Chapman, N. Zatsepin, G. Nelson, U. Weierstall, J. Spence, P. Schwander, L. Pollack, P. Fromme, A. Ourmazd, G.N. Phillips Jr., M. Schmidt (2017) Structural Enzymology Using X-ray Free Electron Lasers, Structural Dynamics, 4, 044003.
  47. C. D. M. Hutchison, J. Tenboer, C. Kupitz, K. Moffat, M. Schmidt, J. J. van Thor (2016) Photocycle Populations with Femtosecond Excitation of Crystalline Photoactive Yellow Protein, J. Chem. Phys. Lett. 654, 63-71.
  48. P. Edlund, H. Takala, E. Claesson, L. Henry, R. Dods, H. Lehtivuori, M. Panman, K. Pande, T. White, T. Nakane, O. Berntsson, E. Gustavsson, P. Bath, V. Modi, S. Roy-Chowdhury, J. Zook, P. Berntsen, S. Pandey, I. Poudyal, J. Tenboer, C. Kupitz, A. Barty, P. Fromme, J. D. Koralek, T. Tanaka, J. Spence, M. Liang, M. S. Hunter, S. Boutet, E. Nango, K. Moffat, G. Groenhof, J. Ihalainen, E. A. Stojkovic, M. Schmidt*, S. Westenhoff* (2016), The room temperature crystal structure of a bacterial phytochrome determined by serial femtosecond crystallography, Scientific reports 6, 35279. *co-corresponding
  49. K. Pande, C. D. M. Hutchison, G. Groenhof, A. Aquila, J. S. Robinson, J. Tenboer, S. Basu, S. Boutet, D. P. DePonte, M. Liang, T. A. White, N. A. Zatsepin, O. Yefanov, D. Morozov, D. Oberthuer, C. Gati, G. Subramanian, D. James, Y. Zhao, J. Koralek, J. Brayshaw, C. Kupitz, C. Conrad, S. Roy-Chowdhury, J. D. Coe, M. Metz, P. L. Xavier, T. E. Grant, J. E. Koglin, G. Ketawala, R. Fromme, V. Šrajer, R. Henning, J. C. H. Spence, A. Ourmazd, P. Schwander, U. Weierstall, M. Frank, P. Fromme, A. Barty, H. N. Chapman, K. Moffat, J. J. van Thor, M. Schmidt(2016) Femtosecond Structural Dynamics Initiates the Trans/Cis Isomerization in Photoactive Yellow Protein, Science 352, 725-729, DOI: 10.1126/science.aad5081.
  50. K. Ayyer, O. Yefanov, D. Oberthuer, S. Roy-Chowdhury, L. Galli, V. Mariani, S. Basu, J. Coe, C. Conrad, R. Fromme, K. Dorner, M. Frank, D. James, C. Kupitz, M. Metz, G. Nelson, X. L. Paulraj, K. Beyerlein, M. Schmidt, I. Sarrou, J. Spence, U. Weierstall, T. White, J. Yang. N. Zatsepin, Y. Zhao, M. Liang, A. Aquila, M. Hunter, J. Robinson, J. Koglin, S. Boutet, P. Fromme, A. Barty, H. Chapman (2016) Macromolecular imaging using disordered crystals, Nature 530, 202-206, DOI: dx.doi.org/10.1038/nature16949.
  51. P. Abbamonte …, M. Schmidt, … P. Zwart (2015, c.a. 240 authors) New science opportunities enabled by LCLS-II X-ray lasers. SLAC-R-1053, SLAC National Accelerator Laboratory.
  52. M. Schmidt (2015) Time-resolved crytallography at X-ray Free Electron Lasers and Synchrotron Light Sources, Synchrotron Radiation News 28(6), 25-30.
  53. A.S. Pawate, V. Srajer, J. Schieferstein, S. Guha, R. Henning, I. Kosheleva, M. Schmidt, Z. Ren, P.J.A. Kenis, S.L. Perry (2015) Towards Time-Resolved Serial Crystallography in a microfluidic device. Acta Crystallogr. F71, 823-830.
  54. M. Schmidt, K. Pande, S. Basu, J. Tenboer (2015) Room temperature structures beyond 1.5 A by serial femtosecond crystallography. Structural Dynamics 2, 041708, 1-9.
  55. Research Highlight (2015), XFELs probe protein dynamics, Nature Methods 12, 109.
  56. K. Pande, M. Schmidt, P. Schwander, D. Saldin (2015) Simulations on Time-Resolved Structure Determination of Uncrystallized Biomolecules in the Presence of Shot Noise. Structural Dynamics 2, 024103, 1-13.
  57. J. Tenboer, S. Basu, N. Zatsepin, K. Pande, D. Milathianaki, M. Frank, M. Hunter, S. Boutet, G. Williams, J. E. Koglin, D. Oberthuer, M. Heymann, C. Kupitz, C. Conrad, J. Coe, S. Roy-Chowdhury, U. Weierstall, D. James, D. Wang, T. Grant, A. Barty, O. Yefanov, J. Scales, C. Gati, C. Seuring, V. Srajer, R. Henning, P. Schwander, R. Fromme, A. Ourmazd, K. Moffat, J. Van Thor, J. H. C. Spence, P. Fromme, H. Chapman, M. Schmidt (2014) Time Resolved Serial Femtosecond Crystallography Captures High Resolution Intermediates of Photoactive Yellow Protein, Science 346 (6214) 1242-1246.
  58. K. Pande, P. Schwander, M. Schmidt, D. Saldin (2014) Deducing Difference Electron Densities of Rapid Variations of Photoexcited Biomolecules in Random Orientations Using an X-Ray Laser, Phil. Trans. Royal Soc. B, Biological sciences 369(1647).
  59. V. Malik, S. Sen, D. Geltin, M. Gajdardziska-Josifovska, M. Schmidt, P. Guptasarma (2014) Magnetic poling induced ferromagnetic-like magnetism in antiferromagnetic nanoparticles. Mater. Res. Express 1 026114.
  60. J. van Thor, M. Warren, C. N. Lincoln, M. Chollet, H. T. Lemke, D. M. Fritz, M. Schmidt, J. Tenboer, Z. Ren, V. Srajer, K. Moffat, T. Graber (2014) Signal to noise considerations for single crystal femtosecond time resolved crystallography of the Photoactive Yellow Protein, Faraday Discussions, DOI: 10.1039/CAFD00011K.
  61. M. Schmidt, D. Saldin (2014) Enzyme transient state kinetics in crystal and solution from the perspective of a time-resolved crystallographer. Structural Dynamics 1, 024701-13.
  62. Y.O. Jung, J.H. Lee, J. Kim, M. Schmidt, K. Moffat, V. Srajer, H. Ihee (2014) Reconciling contradictions in time-resolved X-ray structures of early intermediates in the photocycle of photoactive yellow protein, Nature Chemistry 6(4):259-60.
  63. M. Schmidt, V. Srajer, R. Henning, H. Ihee, N. Purwar, J. Tenboer, S. Tripathi (2013) Protein Energy Landscapes Determined by 5-Dimensional Crystallography, Acta Cryst. D69, 2534–2542, (on the arXiv since July 2013).
  64. N. Purwar, J. Tenboer, S. Tripathi, M. Schmidt (2013) Spectroscopic studies of model photoreceptors: Validation of a nanosecond time-resolved micro-spectrophotometer design using photoactive yellow protein and alfa-phycoerythrocyanin. Intl. J. Mol Sci 14, 18881-18898.
  65. H.-C. Poon, M. Schmidt, D. Saldin (2013) Extraction of Fast Changes in the Structure of a Disordered Ensemble of Photoexcited Biomolecules. Advances in Condensed Matter Physics, 2013, 1-5.
  66. M. Schmidt (2013) Mix and Inject: Reaction Initiation by Diffusion for Time-Resolved Macromolecular Crystallography. Advances in Condensed Matter Physics, 2013, 1-10.
  67. Y. O. Jung, J. H. Lee, J. Kim, M. Schmidt, K. Moffat, V. Srajer, H. Ihee (2013) Volume-conserving trans-cis isomerization pathways in photoactive yellow protein visualized by picosecond X-ray crystallography. Nature Chemistry 5, 212–220.
  68. V. Malik, L. He., Y. Yin, M. Schmidt (2012) Colloidal crystallization and phase transition in suspensions of silica/magnetite core-shell nanoparticles, Langmuir 28 (41), 14777-14783.
  69. M. Youngblut, E.T. Judd, V. Srajer, B. Sayerd, T. Goeltzer, S.J. Elliot, M. Schmidt, A.A. Pacheco (2012) Laue structure of Shewanella oneidensis cytochrome-c nitrite reductase from a high-yield expression system, Journal of Biological Inorganic Chemistry 17 , 647-672.
  70. M. Schmidt, V. Srajer, N. Purwar, S. Tripathi (2012) The kinetic dose limit in room temperature time-resolved Laue crystallography, J. Synch. Rad. 19, 264-273.
  71. T. Tripathi, V. Srajer, N. Purwar, R. Henning, M. Schmidt (2012) pH dependence of the PYP photocycle, Biophys. J. 102 (2), 325-332.
  72. D.K. Saldin, H.-C.Poon, M. Schmidt (2011) Reconstructing an icosahedral virus from single particle diffraction experiments, Opt. Express. 19 , 17318-17335.
  73. N. Purwar, J. McGarry, J. Kostera, A. Pacheco, M. Schmidt (2011) Interaction of Nitric Oxide with Catalase: Structural and Kinetic Analysis, Biochemistry, 50, 4491-4503.
  74. A. Ulijasz, N. Purwar, V. Srajer, M. Schmidt (2010) Biological, macromolecular switches and cyclers, Rom. J. Biochem, 47 (2), 155-164.
  75. M. Schmidt, T. Graber, R. Henning, V. Srajer (2010) Five dimensional crystallography, Acta Cryst A, 66(2), 198.
  76. Y. Zhao and M. Schmidt (2009) The “new SVD4TX”, user friendly software for time-resolved crystallography, J. appl. Cryst., 42, 734-740.
  77. V. Rajcu, M. Schmidt, M. Stoneman (2009) Structural dynamics and kinetics of myoglobin-CO binding: lessons from time-resolved X-ray diffraction and four-wave mixing spectroscopy, in: Biochemical Applications of Nonlinear Optical Spectroscopy (V. Yakovlev ed.), series: optical science and engineering, v. 138 , CRC press, pp 1-32.
  78. M. Schmidt, V. Prusakov, K. Achterhold, F. Parak (2009) Nitrophorin IV: Protein dynamics of a beta-sheet protein, Eur. Biophys. J. 38, 687-700.
  79. M. Schmidt (2008) Structure based enzyme kinetics by time-resolved X-ray crystallography, in: Ultrashort Laser Pulses in Medicine and Biology (eds: W. Zinth, M. Braun, P. Gilch). Springer Verlag, pp 201-241.
  80. F. Parak, K. Achterhold, S. Croci, M. Schmidt (2007) A physical picture of protein dynamics and conformational changes. J. Biol. Phys. 33, 371-387.
  81. M. Schmidt, A. Patel, Yi Zhao, W. Reuter (2007) Structural basis for the photochemistry of a-phycoerythrocyanin. Biochemistry 46 , 416-423.
  82. F. Parak, K. Achterhold, M. Schmidt, V. Prusakov, S. Croci (2006) Protein dynamics on different time scales. Journal of Non-Crystalline Solids 352 , 4371-4378.
  83. M. Schmidt, A. Krasselt, W. Reuter (2006b) Local flexibility of a protein substructure as a prerequisite for reversible c hromophore i somerization of a-phycoerythrocyanin. BBA 1764 , 55-62.
  84. M. Schmidt, K. Nienhaus, R. Pahl, A. Krasselt, U. Nienhaus, F. Parak, V. Srajer (2005a) Ligand migration pathway and protein dynamics in myoglobin: A time-resolved crystallographic study on L29W MbCO. Proc. Nat’l. Acad. Sci. USA 13 , 11704-11709.
    see also: Virtual Journal of Biological Physics Research, a multijournal compilation of the latest research on biological physics, Volume 10, Issue 5.
  85. H. Ihee, S. Rajagopal, V. Srajer, R. Pahl, M. Schmidt, F. Schotte, P.A. Anfinrud, M. Wulff, K. Moffat (2005) Visualizing c hromophore i somerization in photoactive yellow protein from nanoseconds to seconds by time-resolved crystallography. Proc. Nat’l. Acad. Sci. USA 102 , 7145-7150 (feature article).
  86. K. Nienhaus, A. Ostermann, U. Nienhaus, F. Parak, M. Schmidt (2005) Ligand migration and protein fluctuations in myoglobin mutant L29W. Biochemistry 44 , 5095-5105.
  87. M. Schmidt, R. Pahl, H. Ihee, V. Srajer (2005) Protein ligand interaction probed by time-resolved X-ray structure determination. In: Methods in Molecular Biology, Vo. 305, protein-ligand interactions: Methods and Applications (G.U. Nienhaus ed.). Humana Press, Totowa , NJ , pp. 115-154.
  88. S. Rajagopal, S. Anderson, V. Srajer, M. Schmidt, R. Pahl, K. Moffat (2005) A structural pathway for signaling in the E46Q mutant of photoactive yellow protein
  89. S. Rajagopal, M. Schmidt, S. Anderson, H. Ihee, K. Moffat (2004) Analysis of experimental time-resolved crystallographic data by singular value decomposition, Acta Cryst. D60 , 860-871.
  90. M. Schmidt, R. Pahl, S. Anderson V. Srajer, Z.Ren, K. Moffat (2004) Protein Kinetics: Structures of intermediates and reaction mechanism by time-resolved X-ray crystallography. Proc. Nat’l. Acad. Sci. USA 101 , 4799-4804.
  91. M. Schmidt, S. Rajagopal., Z. Ren., K. Moffat (2003) Application of Singular Value Decomposition to the Analysis of Time-Resolved Macromolecular X-ray Data. Biophys. J. 84 , 2112-2129.
  92. V. Srajer, Z. Ren, T.Y. Teng, M. Schmidt, T.Ursby, D. Bourgeois, C. Pradervand, W. Schildkamp., M.Wulff., K. Moffat (2001) Protein Conformational Relaxation and Ligand Migration in Myoglobin: A ns-ms molecular movie from time-resolved X-ray diffraction. Biochem. 40 , 13802-13815.
  93. B. Perman, S. Anderson, M. Schmidt, K. Moffat (2000) New techniques in fast time-resolved structure determination. Cell. Mol. Biol. 46(5) , 895-913.
  94. V. Srajer, S. Crosson, M. Schmidt, J. Key, F. Schotte, S. Anderson, B. Perman, Z. Ren, T.Y. Teng, K. Moffat, D. Bourgeois, F. Schotte, M. Wulff (2000) Extraction of accurate structure factor amplitudes from Laue data: wavelength normalization with wiggler and undulator X-ray sources. J. Synchrotron Rad. 7, 236-244.
  95. M. Schmidt, A. Battistone, A. Desideri, F. Parak (1999) X-ray structure analysis of the K175I mutant of the superoxid dismutase from P. shermanii. Perspectives in Structural Biology, ed.:Vijayan M., Yathindra N., Kolaskar A.S;Univ.Press India, Hyderabat, 83-97.
  96. M. Schmidt (1999) Manipulating the coordination number of the ferric iron within the cambialistic superoxide dismutase of Propionibacterium shermanii by changing the pH value – A crystallographic analysis – Europ. J. Biochem. 262 , 117-127.
  97. B. Meier, C. Scherk, M. Schmidt, F. Parak (1998) pH dependent inhibition by azide and fluoride of the iron superoxide dismutase from Propionibacterium shermanii. Biochem J. 331 , 403-407.
  98. M. Schmidt, C. Scherk, O. Jakovleva, B. Meier O., H.F. Nolting, F. Parak (1998) The structure of the azide coordinated superoxide dismutase of P. shermanii investigated by X-ray structure analysis, EXAFS, Mössbauer- and EPR spectroscopy. Inorg. chim. acta 275-276 , 65-72.
  99. R. Gabbianelli, A. Battistoni, F. Polticelli, B. Meier, M. Schmidt, G. Rotilio, A. Desideri (1997) Effect of Lys175 mutation on structure-function properties of Propionibacterium shermanii superoxide dismutase. Prot. Ing. 10 , 1067-1070.
  100. M. Schmidt, B. Meier, F. Parak (1996) X-ray structure of the cambialistic superoxide dismutase from Propionibacterium shermanii active with Fe or Mn. J. biol. inorg. chem. 1 , 523-541.
  101. C. Scherk, M. Schmidt, H.-F. Nolting, B. Meier, F. Parak (1996) EXAFS investigations on the active site of iron superoxide dismutase of Escherichia coli and Propionibacterium shermanii. Eur. Biophys. J. 24 , 243-250.
  102. M. Schmidt, C. Scherk, B. Meier, H.F. Nolting, F. Parak (1996) Investigations on a superoxide dismutase of Propionibacterium shermanii by X-ray absorption spectroscopy and X-ray crystallography. J. Inorg. Biochem. 59, 375.
  103. M. Schmidt, F. Parak, G. Corongiu (1996) Density distributions in the water shell of myoglobin. Int. J. Quant. Chem. 59 , 263-269.
  104. F. Parak, H. Hartmann, M. Schmidt, G. Corongiu (1993) The hydration shell of myoglobin molecules. Conf. Proc. Vol. 43 “water biomolecule interactions”, M.U. Palma, M.U. Palma-Vitorelli, F. Parak (eds.) SIF, Bologna, 115-122.
  105. F. Parak, H. Hartmann, M. Schmidt, G. Corongiu, E. Clementi (1992) The hydration shell of myoglobin. Eur. Biophys. J. 21 , 313-320.

Conference Proceedings, Others

  1. M. Schmidt (2021) SPB/SFX Highlight, Antibiotic Resistance Captured on Film, in: European XFEL annual report 2021, p. 20 – 22, see XFEL Annual Reports.
  2. M. Schmidt (2020) SPB/SFX Highlight, Making Molecular Movies at the European XFEL, in: European XFEL annual report 2019, p. 12 – 13, see XFEL Annual Report 2019 and First Movies at EuXFEL , also available in German: Erste molekulare Filme am Europeaischen XFEL .
  3. K. Ayyer, O. Yefanov, D. Oberthuer, S. Roy-Chowdhury, L. Galli, V. Mariani, S. Basu, J. Coe, C. Conrad, R. Fromme, K. Dorner, M. Frank, D. James, C. Kupitz, M. Metz, G. Nelson, X. L. Paulraj, K. Beyerlein, M. Schmidt, I. Sarrou, J. Spence, U. Weierstall, T. White, J. Yang. N. Zatsepin, Y. Zhao, M. Liang, A. Aquila, M. Hunter, J. Robinson, J. Koglin, S. Boutet, P. Fromme, A. Barty, H. Chapman (2015) Improving resolution in serial crystallography, Preview Article, Acta Cryst A.
  4. J. Tenboer, S. Basu, N. Zatsepin, K. Pande, D. Milathianaki, M. Frank, M. Hunter, S. Boutet, G. Williams, J. E. Koglin, D. Oberthuer, M. Heymann, C. Kupitz, C. Conrad, J. Coe, S. Roy-Chowdhury, U. Weierstall, D. James, D. Wang, T. Grant, A. Barty, O. Yefanov, J. Scales, C. Gati, C. Seuring, V. Srajer, R. Henning, P. Schwander, R. Fromme, A. Ourmazd, K. Moffat, J. Van Thor, J. H. C. Spence, P. Fromme, H. Chapman, H. Ihee, N. Purwar, S. Tripathi, M. Schmidt (2015) Time-Resolved Macromolecular Crystallography at Synchrotron and X-ray FEL, ACA meeting, Philadelphia.
  5. M. Schmidt, V. Srajer, R. Henning, H. Ihee, N. Purwar, J. Tenboer, S. Tripathi (2013). Real-Time Capture of Intermediates and Barriers of Activation in Enzymatic Reactions. APS Highlights Dec 2013.
  6. Schmidt M (2012) Buerger Award Lecture. ACA reflections:15.
  7. M. Schmidt, Wang Y-X (2012) Emerging Sources: Theory and Practice I, ACA Reflections: 15-16.
  8. M. Schmidt (2012) Report on Buerger Award Lecture by J. Spence, ACA Reflections 15.
  9. N. Purwar, J. McGarry, A. Pacheco, M. Schmidt (2010) An X-ray crystallographic investigation of nitic oxide binding to beef liver catalase. ACA 2010, Abstract S-138.
  10. M. Schmidt, T. Graber, R. Henning, V. Srajer (2010) 5-dimensional crystallography, ACA 2010, Abstract T-003.
  11. F.G. Parak, K. Achterhold, M. Schmidt (2005) Protein dynamics in very different time-windows. Eur. Biophys J. 34: 621.
  12. M. Schmidt, F. Parak, G.U. Nienhaus, K. Nienhaus, K. Moffat, S. Rajagopal, H. Ihee, V. Srajer (2005) Structures of intermediates, functional relaxations and kinetics from time-resolved X-ray data. Eur. Biophys. J. 34: 572.
  13. M. Schmidt, F. Parak, G.U. Nienhaus, K. Nienhaus, K. Moffat, S. Rajagopal, H. Ihee, V. Srajer (2005) Structures of intermediates, functional relaxations and kinetics from time-resolved X-ray data. Eur. Biophys. J. 34: 814.
  14. V.E. Prusakov, W. Gutscher, M. Schmidt, F.G. Parak (2005) Nitrophorin 4, protein dynamics in a beta-sheet protein. Eur. Biophys. J. 34: 622.
  15. M. Schmidt, S. Rajagopal, S. Anderson, K. Moffat (2004) Protein Kinetics: Relaxations on the atomic length scale. Acta Cryst A60, 19.
  16. M. Schmidt, A. Krasselt, F. Parak, U. Nienhaus, K. Nienhaus, V. Srajer, R. Pahl (2004) Functional Relaxations determined by Protein Kinetics. Acta Cryst A60, 124.
  17. A. Krasselt, M. Schmidt, W. Reuter (2004) Towards time-resolved studies with Phycoerythrocyanin (PEC)-crystals from Mastigocladus laminosus. Acta Cryst A60, 129.
  18. M. Schmidt, R. Pahl, V. Srajer, S. Anderson, Z. Ren, H. Ihee, K. Moffat (2003) Transient state protein kinetics by time-resolved macromolecular X-ray crystallography. Eur. Biophys. J. 32: 243.
  19. K. Moffat, V. Srajer, R. Pahl, Z. Ren, M. Schmidt, S. Anderson, S. Crosson, B. Perman, S. Rajagopal, H. Ihee, D. Bourgeois & M. Wulff (2002). Time-resolved macromolecular crystallography: molecular movies?. Acta Cryst. A58, C27.
  20. S. Anderson, V. Srajer, R. Pahl, H. Ihee, S. Rajogopal, S. Crosson, M. Schmidt, F. Schotte, P. A. Anfinrud, M. Wulff & K. Moffat (2002). Structural intermediates in the photocycle of E46Q mutant photoactive yellow protein. Acta Cryst. A58, C241.
  21. M. Schmidt, R. Pahl, V. Srajer, S. Anderson, K. Brister, S. Ruan, S. Rajagopal, Z. Ren & K. Moffat (2002). Application of singular value decomposition to time-resolved X-ray data; simulations and experiments. Acta Cryst. A58, C374.
  22. Faraday discussions 122, Manchester, U.K. , (2002) J. Chem. Soc. Farad. Trans. The Application of SVD to Time-Resolved X-ray Data.
  23. M. Schmidt, S. Rajagopal, Z. Ren, K. Moffat (2001) Singular Value Decomposition (SVD) in Time Resolved Macromolecular X-ray Structure Determination. DGFB Jahrestagung, Münster (Posterpreis).
  24. M. Schmidt, C. Scherk, A. Desideri, F. Parak (1999) How to inhibit the cambialistic SOD of P.shermanii containing iron – a structural analysis – ICBIC 99, Minneapolis, J. Inorg. Biochem. 74: 288.
  25. M. Schmidt, B. Meier, F. Parak (1997) The structure of the azide coordinated superoxide dismutase (SOD) of P. shermanii. Europ. Biophys. J. 26(1): 35.
  26. C. Scherk, M. Schmidt, H.-F. Nolting, B. Meier, F. Parak (1997) Comparing iron and manganese specifity of the active center of superoxide dismutase of P. shermanii. Eur. Biophys. J. 26(1): 35.
  27. M. Schmidt, C. Scherk, B. Meier, O. Iakovleva, F. Parak (1996) The structure of the superoxide dismutase of Propionibacterium shermanii. Investigations by X-ray structure analysis, EXAFS, Mössbauer- and EPR spectroscopy. Proceedings of the 3rd european conference on bio-inorganic chemistry, M.C. Feiters, W.R. Hagen, C. Veeger (eds.), F21.
  28. B. Meier, M. Schmidt, F. Parak (1996) Inhibition of an iron superoxide dismutase from Propionibacterium shermanii by azide or fluoride: pH-dependence. Proceedings of the 3-rd European Conference on Bio-inorganic Chemistry. M.C. Feiters, W.R. Hagen, C. Veeger (eds.), F18.
  29. Schmidt M., Meier B., Scherk C., Iakovleva O., Parak F. (1996) The cambialistic superoxide dismutase of P. shermanii; X-ray structure and spectroscopic investigations. XIIth International Biophysics congress.
  30. Schmidt M., Meier B., Scherk C., Iakovleva O., Parak F. (1996) The cambialistic superoxide dismutase (SOD) of P. shermanii; X-ray structure and spectroscopic investigations. Prog. Biophys. molec. Biol 65(1): 31.
  31. Scherk C., Schmidt M., Meier B., Parak F., Nolting H.F. (1996) EXAFS investigations on the SOD of P.shermanii and on a model compound. HASYLAB Jahresbericht.
  32. Scherk C., Schmidt M., Parak F., Nolting H.F. (1995) pH dependence of the active center of the SOD of P.shermanii. HASYLAB.

Contributions to the Protein Data Bank:

6BAF, 6BAK, 6BAO, 6BAP, 6BAY, 6B5X, 6B5Y, 6B68, 6B69, 6B6A, 6B6B, 6B6C, 6B6D, 6B6E, 3UBR, 3ER8, 3RGP, 3RGS, 2J96, 2C7J, 2C7K, 2C7L, 2BWH, 2BW9, 1TS0, 1TS6, 1TS7, 1TS8, 2BLH, 2BLI, 2BLJ, 1T18, 1T19, 1T1A, 1T1B, 1T1C, 1S4R, 1S4S, 1BS3, 1BSM, 1BT8, 1AVM, 1AR4, 1AR5 … more