Publications

J. N. Milstein, D. F. Nino, X. Zhou, & C. C. Gradinaru, Single-molecule counting applied to the study of GPCR oligomerization. Biophysical Journal, (2021). 121

E. Zapata-Mercado, G. Biener, D. M. McKenzie, W. C. Wimley, E. B. Pasquale, V. Raicu, & K. Hristova, The efficacy of receptor tyrosine kinase EphA2 autophosphorylation increases with EphA2 oligomer size. Journal of Biological Chemistry, (2022). 102370

S. Marsango, L. Jenkins, J. D. Pediani, S. J. Bradley, R. J. Ward, S. Hesse, G. Biener, M. R. Stoneman, A. B. Tobin, V. Raicu, & G. Milligan, The M1 muscarinic receptor is present in situ as a ligand-regulated mixture of monomers and oligomeric complexes. Proceedings of the National Academy of Sciences 119 24, (2022). e2201103119

R. J. Ward, J. D. Pediani, S. Marsango, R. Jolly, M. R. Stoneman, G. Biener, T. M. Handel, V. Raicu, & G. Milligan, Chemokine receptor CXCR4 oligomerization is disrupted selectively by the antagonist ligand IT1t. Journal of Biological Chemistry 269, (2021). 100139

M. R. Stoneman, G. Biener, & V. Raicu, Reply to: Spatial heterogeneity in molecular brightness. Nature Methods 17, (2020). 276–278

M. R. Stoneman, G. Biener, R. J. Ward, J. D. Pediani, D. Badu, A. Eis, I. Popa, G. Milligan, and V. Raicu, A general method to quantify ligand-driven oligomerization from flourescence-based images Nature Methods (2019)

J.D. Pediani, R.J. Ward, S. Marsango, G. Milligan, Spatial intensity distribution analysis: studies of G protein-coupled receptor oligomerisation, Trends in Pharmacological Sciences, 39 (2018) 176-186

R.J. Ward, J.D. Pediani, K.G. Harikumar, L.J. Miller, G. Milligan, Spatial intensity distribution analysis quantifies the extent and regulation of homodimerization of the secretin receptor, Biochemical Journal, 474 (2017) 1879-1895

K. King, V. Raicu, K. Hristova, Understanding the FRET signatures of Interacting Membrane Proteins, Journal of Biological Chemistry, 292 (2017) 5291-5310, doi: 10.1074/jbcM116.764282

A.K. Mishra, M. Gragg, M.R. Stoneman, G. Biener, J.A. Oliver, P. Miszta, S. Filipek, V. Raicu, P. Park, Quaternary structures of opsin in live cells revealed by FRET spectrometry, Biochemical Journal, 473 (2016) 3819-3836

C. King, M.R. Stoneman, V. Raicu, K. Hristova. Fully quantified spectral imaging reveals in vivo membrane protein interactions, Integrative Biology, 8 (2016) 216-229

S. Patowary, L.F. Pisterzi, J.D. Holz, J.A. Oliver, J.W. Wells, V. Raicu, Experimental verification of the kinetic theory of Förster resonance energy transfer using optical micro-spectroscopy and obligate oligomers expressed in living cells, Biophysical Journal, 108 (2015) 1613-1622

S. Patowary, E. Alvarez-Curto, T.R. Xu, J.D. Holz, J. Oliver, G. Milligan, V. Raicu, The muscarinic M3 acetylcholine receptor exists as two differently sized complexes at the plasma membrane, Biochemical Journal, 452 (2013) 303-312

L.F. Pisterzi, D.B. Jansma, J. Georgiou, M.J. Woodside, J.T-C Chou, S. Angers, V. Raicu, J.W. Wells, Oligomeric size of the M2 muscarinic receptor in live cells as determined by quantitative fluorescence resonance energy transfer (FRET), Journal of Biological Chemistry, 285 (2010) 16723-16738

V. Raicu, M.R. Stoneman, R. Fung, M. Melnichuk, D.B. Jansma, S. Rath, L.F. Pisterzi, M. Fox, J.W. Wells, D.K. Saldin, Determination of the supramolecular structure and spatial distribution of protein complexes in living cells, Nature Photonics 3 (2009) 107-113