Books
2. V. Raicu and Yuri Feldman (Editors), Dielectric Relaxation of Biological Systems: Physical Principles, Methods and Applications, Oxford University Press (2015)
1. V. Raicu and A.I. Popescu Integrated Cellular and Molecular Biophysics, Springer (2008)
Book Chapters
9. V. Raicu and William F. Schmidt, Advanced Microscopy Techniques, In: Katharine Herrick-Davis, Graeme Milligan, Giuseppe Di Giovanni (Editors), G Protein-Coupled Receptor Dimers, Springer (2017)
8. V. Raicu, Sekine, K., Asami, K., Dielectric Models and Computer Simulations for Complex Aggregates, In: V Raicu and Y. Feldman (Editors), Dielectric Relaxation in Biological Systems, Oxford University Press (2015)
7. Y. Feldman, Ben Ishai, P., Raicu, V. Electrode Polarization, In: V Raicu and Y. Feldman (Editors), Dielectric Relaxation in Biological Systems, Oxford University Press (2015)
6. Y. Feldman, Ben Ishai, P., Puzenko, A., Raicu, V., Elementary Theory of the Interaction of Electromagnetic Fields with Dielectric Materials, In: V Raicu and Y. Feldman (Editors),Dielectric Relaxation in Biological Systems, Oxford University Press (2015)
5. U. Kaatze, Feldman, Y., Ben Ishai, P., Greenbaum-Gutina, A., Raicu, V, Experimental Methods, In: V Raicu and Y. Feldman (Editors), Dielectric Relaxation in Biological Systems, Oxford University Press (2015)
4. Ermolina, I., Hayashi, Y., Raicu, V., Feldman, Y., Proteins in Solutions and Natural Membranes, In: V Raicu and Y. Feldman (Editors), Dielectric Relaxation in Biological Systems, Oxford University Press (2015)
3. V. Raicu, Theory of Suspensions of Particles in Homogeneous Fields, In: V Raicu and Y. Feldman (Editors), Dielectric Relaxation in Biological Systems, Oxford University Press (2015)
2. V. Raicu, FRET-based determination of protein complex structure at nanometer length scale in living cells, In: A. Diaspro (Editor), Nanoscopy and Multidimensional Optical Fluorescence Microscopy, Chapman & Hall/CRC (2010)
1. V. Raicu, M. Schmidt, M.R. Stoneman, Structural dynamics and kinetics of myoglobin-CO binding: time-resolved X-ray diffraction and four-wave mixing, In: V. Yakovlev (Editor), Biochemical Applications of Nonlinear Optical Spectroscopy, CRC (2009)
Papers
78. E. Zapata-Mercado, G. Biener, D. M. McKenzie, W. C. Wimley, E. B. Pasquale, V. Raicu, & K. Hristova, The efficacy of receptor tyrosine kinase EphA2 autophosphorylation increases with EphA2 oligomer size. Journal of Biological Chemistry, (2022) 102370
77. S. Marsango, L. Jenkins, J. D. Pediani, S. J. Bradley, R. J. Ward, S. Hesse, G. Biener, M. R. Stoneman, A. B. Tobin, V. Raicu, & G. Milligan, The M1 muscarinic receptor is present in situ as a ligand-regulated mixture of monomers and oligomeric complexes. Proceedings of the National Academy of Sciences 119 24, (2022) e2201103119
76. V. Raicu, Potentials induced by applied electrical fields in and around particles comprised of four dielectric layers. Bioelectrochemistry 144, (2022) 108039
75. T. D. Killeen, S. Rahman, D. N. Badu, G. Biener, M. R. Stoneman, & V. Raicu, Fluorescence Intensity Fluctuation Analysis of Protein Oligomerization in Cell Membranes. Current Protocols (2022)
74. D. P. Adhikari, G. Biener, M. R. Stoneman, D. N. Badu, J. D. Paprocki, A. Eis, P. S-H Park, I. Popa, & V. Raicu, Comparative photophysical properties of some widely used fluorescent proteins under two-photon excitation conditions. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy 262, (2021) 120133
73. G. Biener, M. R. Stoneman, & V. Raicu, Fluorescence intensity fluctuation analysis of receptor oligomerization in membrane domains. Biophysical Journal 120 15, (2021) 3028-3039
72. M. R. Stoneman & V. Raicu, Dielectric Spectroscopy Based Detection of Specific and Nonspecific Cellular Mechanisms. Sensors 21(9), (2021) 3177
71. R. J. Ward, J. D. Pediani, S. Marsango, R. Jolly, M. R. Stoneman, G. Biener, T. M. Handel, V. Raicu, & G. Milligan, Chemokine receptor CXCR4 oligomerization is disrupted selectively by the antagonist ligand IT1t. Journal of Biological Chemistry 296, (2021) 100139
70. J. Trujillo, & V. Raicu, Real time monitoring of the evolution of an epidemic regarded as a physical relaxation process. Physics Letters A 388, (2021) 127074
69. M. R. Stoneman, N. Raicu, G. Biener, & V. Raicu, Fluorescence-based methods for the study of protein-protein interactions modulated by ligand binding. Current Pharmaceutical Design 26, (2020) 5668 – 5683
68. J. D. Paprocki, G. Biener, M. R. Stoneman & V. Raicu, In-cell detection of conformational substates of a G protein-coupled receptor quaternary structure: Modulation of substate probability by cognate ligand binding. Journal of Physical Chemistry B 124, (2020) 10062 – 10076
67. B. Vanderhoof, R. Nelson, G. Biener, V. Raicu, & J. Oliver, Tissue factor oligomerization in living cells using Förster resonance energy transfer. Microscopy and Microanalysis 26, (2020) 828 – 829
66. M. R. Stoneman, G. Biener, & V. Raicu, Proposal for simultaneous analysis of fluorescence intensity fluctuations and resonance energy transfer (IFRET) measurements. Methods and Applications in Fluorescence 8, (2020) 0335011
65. M. R. Stoneman, G. Biener, & V. Raicu, Reply to: Spatial heterogeneity in molecular brightness. Nature Methods 17, (2020) 276–278
64. M. R. Stoneman, G. Biener, R. J. Ward, J. D. Pediani, D. Badu, A. Eis, I. Popa, G. Milligan, and V. Raicu, A general method to quantify ligand-driven oligomerization from flourescence-based images Nature Methods (2019)
63. V. Raicu, Ab Initio Derivation of the FRET Equations Resolves Old Puzzles and Suggest Measurement Strategies Biophysical Journal 116 (2019) 1313-1327
62. Dammar N. Badu, Koki Yokoi, and V. Raicu, Relaxation in systems with hierarchical organization: Analytical derivation of the relaxation and dispersion functions. Physics Letters A 383 (2019) 1063-1170
61. C. Ghosh, L. Sathe, J.D. Paprocki, V. Raicu, and M. Dey, Adaptation to Endoplasmic Reticulum Stress Requires Transphosphorylation within the Activation Loop of Protein Kinases Kin1 and Kin2, Orthologs of Human Microtubule Affinity-Regulating Kinase. Molecular Cellular Biology 38 (2018) e00266-18
60. V. Raicu, Extraction of information on macromolecular interactions from fluorescence micro-spectroscopy measurements in the presence and absence of FRET. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy 199 (2018) 340-348
59. MJ Corby, M.R. Stoneman, G. Biener, J.D. Paprocki, R. Kolli, V. Raicu, D.N. Frick, Quantitative micro-spectroscopic imaging reveals viral and cellular RNA helicase interactions in live cells. Journal of Biological Chemistry 292 (2017) 11165-11177
58. J. Huang, Z. Li, G. Biener, E. Xiong, S. Malik, N. Eaton, C.Z. Zhao, V. Raicu, H. Kong, and D. Zhao, Carbonic Anhydrases Function in Anther Cell Differentiation Downstream of the Receptor-like Kinase EMS1. The Plant Cell 29 (2017) 1335-1356
57. Koki Yokoi and V. Raicu, Investigation of dielectric relaxation in systems with hierarchical organization: From time to frequency domain and back again, Physics Letters A 381 (2017) 1981-1988
56. G. Biener, D. Masson-Meyers, V.V. Bumah, C.S. Enwemeka. and V. Raicu, Blue/violet laser inactivates methicillin-resistant Staphylococcus aureus by altering its transmembrane potential, Journal of Photochemistry and Photobiology B: Biology 170 (2017) 118-124
55. K. King, V. Raicu and K. Hristova, Understanding the FRET signatures of Interacting Membrane Proteins, Journal of Biological Chemistry 292 (2017) 5291-5310
54. M.R. Stoneman, J.D. Paprocki, G. Biener, A. Shevade, S. Kuchin, and V. Raicu, Quaternary structure of the yeast pheromone receptor Ste2 in living cells. BBA Biomembranes 1859 (2017) 1456-1464
53. Z. Li, Y. Wang, J. Huang, N. Ahsan, G. Biener, J. Paprocki, J.J. Thelen, V. Raicu, D. Zhao, Two SERK Receptor-Like Kinases Interact with EMS1 to Control Anther Cell Fate Determination, Plant Physiology 173 (2017) 326-337
52. A.K. Mishra, M. Gragg, M.R. Stoneman, G. Biener, J.A. Oliver, P. Miszta, S. Filipek, V. Raicu, P. Park, Quaternary structures of opsin in live cells revealed by FRET spectrometry, Biochemical Journal 473 (2016) 3819-3836
51. C. King, M.R. Stoneman, V. Raicu, K. Hristova. Fully quantified spectral imaging reveals in vivo membrane protein interactions, Integrative Biology 8 (2016), 216-229
50. X. Yuan, D. Khokhani, X. Wu, F. Yang, G. Biener, B.J. Koestler, V. Raicu, C. He, C.M. Waters, G.W. Sundin, F. Tian, and C.-H. Yang, Cross-talk between a regulatory small RNA, cyclic-di-GMP signaling, and flagellar regulator FlhDC for virulence and bacterial behaviors, Environmental Microbiology 17 (2015) 146
49. D. Masson-Meyers, V.V. Bumah, G. Biener, V. Raicu, C.S. Enwemeka. The relative antimicrobial effect of blue 405 nm LED and blue 405 nm laser on methicillin-resistant Staphylococcus aureus in vitro, Lasers in Medical Science, 30 (2015) 2265-2271
48. S. Patowary, L.F. Pisterzi, G. Biener, J.D. Holz, J.A. Oliver, J.W. Wells, V. Raicu. Experimental verification of the kinetic theory of FRET using optical microspectroscopy and obligate oligomers, Biophysical Journal, 108:7 (2015) 1613-1622
47. A.K. Mishra., T. Mavlyutov, D.R. Singh., G. Biener, J. Yang, J.A. Oliver, A. Ruoho, V. Raicu. The sigma 1 receptors are present in monomeric and oligomeric forms in living cells in the presence and absence of ligands. Biochemical Journal, 466 (2015) 263-271
46. G. Biener, M.R. Stoneman, G. Acbas, J.D. Holz, L. Komorova, M. Orlova, S. Kuchin, V. Raicu, Development and experimental testing of an optical micro-spectroscopic technique incorporating true line-scan excitation, International Journal of Molecular Sciences, 15 (2014) 261-276
45. V. Raicu, D. R. Singh, FRET spectrometry: A New Toll for the Determination of Protein Quaternary Structure in Living Cells, Biophysical Journal 105(2013) 1937-1945
44. M. A. Mannan, W. Shadrick, G. Biener, B. Shin, A. Anshu, V. Raicu, D. Frick, M. Dey, An ire1-phk1 chimera reveals a dispensable role of autokinase activity in endoplasmic reticulum stress response, Journal of Molecular Biology, 425:12 (2013) 2083–2099
43. S. Patowary, E. Alvarez-Curto, T. Xu, J. Holz, J. Oliver, G. Milligan, V. Raicu, The muscarinic M3 acetylcholine receptor exists as two differently sized complexes at the plasma membrane, Biochemical Journal, 452:2 (2013) 303-312
42. D.R. Singh, M.M. Mohammad, S. Patowary, M. Stoneman, J. Oliver, L. Movileanu, V. Raicu, Determination of the quaternary structure of a bacterial ATP-binding cassette (ABC) transporter in living cells, Integrative Biology, 5 (2013) 312-323
41. M. Stoneman, S. Patowary, D.R. Singh, L. Komarova, L. Westrick, J. Oliver, V. Raicu, Quantifying the efficiency of various FRET constructs using OptiMiS, BioTechniques, 52:3 (2012) 191-195
40. M. Stoneman, D.R. Singh, V. Raicu, In-vivo quantification of G protein coupled receptor interactions using spectrally-resolved two-photon microscopy, Journal of Visualized Experiments, 47 (2011); doi: 10.3791/2247
39. M. Habibi, D. Klemer, V. Raicu, Two-dimensional dielectric spectroscopy: Implementation and validation of a scanning open-ended coaxial probe, Review of Scientific Instruments, 81, 075108 (2010)
38. L.F. Pisterzi, D.B. Jansma, J. Georgiou, M.J. Woodside, J.T-C Chou, S. Angers, V. Raicu, J.W. Wells, Oligomeric size of the M2 muscarinic receptor in live cells as determined by quantitative fluorescence resonance energy transfer (FRET), Journal of Biological Chemistry, 285 (2010) 16723–16738
37. D.R. Singh, V. Raicu, Comparison between whole-distribution- and average-based approaches to the determination of FRET efficiency in ensembles of proteins in living cells, Biophysical Journal, 98 (2010) 2127-2135
36. M.R. Stoneman, M. Florescu, M.P. Fox, W.D. Gregory, A. Hudetz, V. Raicu, Non-Debye dielectric behaviour and near-field interactions in biological tissues: when structure meets function, Journal of Non-Crystalline Solids, 356 (2010) 772-776
35. M.R. Stoneman, D.R. Singh and V. Raicu, In vivo stoichiometry monitoring of G protein coupled receptor oligomers using spectrally resolved two-photon microscopy, In: A. Periasamy, P.T.C. So and K. König (Eds.), Multiphoton Microscopy in the Biomedical Sciences X, Proceedings of SPIE, 7569 (2010) 756913-1 – 756913-8
34. M. Habibi, D.P. Klemer, V. Raicu, Implementation of a fast reconfigurable array for tissue impedance characterization,Proceedings of the 31st Annual International Conference of the IEEE EMBS (2009) 2284-2287
33. Rath, S., A. P. Sullivan, M. R. Stoneman and V. Raicu, Microspectroscopic method for determination of size and distribution of protein complexes in vivo, In: M.T. Postek, D.E. Newbury, S.F. Platek and D.C. Joy (Eds.), Scanning Microscopy 2009, Proceedings of SPIE, 7378 (2009) 737829-1 – 737829-7
32. V. Raicu, M.R. Stoneman, R. Fung, M. Melnichuk, D.B. Jansma, S. Rath, L.F. Pisterzi, M. Fox, J.W. Wells, D.K. Saldin, Determination of supramolecular structure and spatial distribution of protein complexes in living cells, Nature Photonics, 3 (2009) 107-113
31. M.R. Stoneman, M. Fox, C. Zeng, V. Raicu, Real-time monitoring of two-photon photopolymerization for use in fabrication of microfluidic devices for biological investigations, Lab on a Chip, 9 (2009) 819-827
30. V. Raicu, A. Chaturvedi, M. Stoneman, R. Fung, D. Saldin, G. Petrov, D. Gillman, Determination of two-photon excitation and emission spectra of fluorescent molecules in single living cells, Proceedings of SPIE, Multiphoton Microscopy in the Biomedical Sciences VIII, Editors: Ammasi Periasamy, Peter T.C. So (2008)
29. M. R. Stoneman, M. Kosempa, W. D. Gregory, C. W. Gregory, J. J. Marx, W. Mikkelson, J. Tjoe, and V. Raicu – Correction of electrode polarization contributions to the dielectric properties of normal and cancerous breast tissues at audio/radio frequencies,Phys. Med. Biol., 52 (2007) 6589-6604
28. V. Raicu – Efficiency of resonance energy transfer in homo-oligomeric complexes of proteins, J. Biol. Phys., 33(2) (2007) 109-127
27. M. R. Stoneman, A. Chaturvedi, D. Jansma, M. Kosempa, C. Zeng, V. Raicu – Protein influence on the plasma membrane dielectric Properties: In vivo study utilizing dielectric spectroscopy and fluorescence microscopy, Bioelectrochemistry, 70 (2007) 542-550
26. M. Balcan, D. F. Anghel, D. Donescu, V. Raicu, The retention behavior of ethoxylated nonionic surfactants in reversed-phase high performance liquid chromatographic systems, Revue Roumaine de Chimie, 52 (8-9) (2007) 771-780
25. V. Raicu, R. Fung, M. Melnichuk, A. Chaturvedi, D. Gillman – Combined spectrally-resolved multiphoton microscopy and transmission microscopy employing a high-sensitivity electron-multiplying CCD camera, Proceedings of SPIE, Multiphoton Microscopy in the Biomedical Sciences VII, Editors: Ammasi Periasamy, Peter T.C. So, 6442 (2007) 64420M-1 – 64420M-5
24. V. Raicu, D. Jansma, K. Michalski, Fluorescent resonance energy transfer – a test bench for fundamental laws of nature in vivo, Proceedings of SPIE, Imaging, Manipulation, and Analysis of Biomolecules, Cells, and Tissues IV, Editors: Daniel L. Farkas, Dan V. Nicolau, Robert C. Leif, 6088 (2006), 60880A-1 – 60880A-9
23. M. Walther, V. Raicu, J.P. Ogilvie, R. Phillips and R.J.D. Miller, Transient phase grating spectroscopy of trehalose embedded myoglobin, J. Phys. Chem. B, 109 (2005) 20605-20611
22. Nagy, V. Raicu and R.J.D. Miller, Nonlinear Optical Studies of Heme Protein Dynamics: Implications for Proteins as Hybrid States of Matter, Biochim. Biophys. Acta, 1749 (2005) 148-172
21. V. Raicu, D.B. Jansma, R.J.D. Miller and J. D. Friesen, Quantification of protein interactions in single cells by spectrally resolved fluorescence resonance energy transfer, Biochem. J., 385 (2005) 265-277
20. M. Balcan, D. F. Anghel and V. Raicu, Phase behavior of water/oil/nonionic surfactants with normal distribution of the poly(ethylene oxide) (PEO) chain length, Colloid Polym. Sci., 280:2 (2003), 143-149
19. Y-J Jin, T. Mima, V. Raicu, K. C. Park, and K. Shimizu, Combined argatroban and edaravone caused additive neuroprotection against 15 minutes of forebrain ischemia in gerbils, Neuroscience Res., 43:1 (2002) 75-79
18. M. Ando, S. Takeuchi, V. Raicu, K.-I. Yagyu and T. Sato, Acute ischemia causes ‘dark cell’ change of strial marginal cells in gerbil cochlea, Cell Tissue Res., 309:2 (2002) 229-235
17. V. Raicu, T. Sato and G. Raicu, Non-Debye dielectric relaxation in biological structures arises from their fractal nature, Phys. Rev. E, 64, 2 (2001) 02191
16. V. Raicu, T, Yamashiro, N. Kitagawa, T. Mima, and T. Sato, Dielectric dispersion of animal tissues: is it Debye-type?, In: Proc. XIth Int. Conf. Electrical Bio-impedance, Editors: S Grimnes, Ø.G. Martinsen, and H. Bruvoll, 2001, 573-577
15. V. Raicu, T. Saibara and A. Irimajiri, Multifrequency method for dielectric monitoring of cold-preserved organs, Phys. Med. Biol., 45 (2000) 1397-1407
14. V. Raicu, N. Kitagawa and A. Irimajiri, A quantitative approach to the dielectric properties of the skin, Phys. Med. Biol., 45 (2000) L1-L4
13. A. Irimajiri, V. Raicu, Characterization of red blood cell aggregation (rouleaux formation) by analysis of whole blood dielectric dispersion (in Japanese), Seibutsu Kogaku Kaishi, 78 (2000) 162-165 (in Japanese)
12. V. Raicu, Dielectric dispersion of biological matter: model combining Debye-type and “universal” responses, Phys. Rev. E 60 (1999) 4677-4680
11. V. Raicu, T. Saibara and A. Irimajiri, Dielectric properties of rat liver in vivo: a noninvasive approach using an open-ended coaxial probe at radio frequencies, Bioelectrochem. Bioenerg., 47 (1998) 325-332
10. V. Raicu, T. Saibara, H. Enzan and A. Irimajiri, Dielectric properties of rat liver in vivo: analysis by modeling hepatocytes in the tissue architecture, Bioelectrochem. Bioenerg., 47 (1998) 333-342
9. V. Raicu, A. Baran, D.F. Anghel, S. Saito, A. Iovescu and C. Radoi, Electrical conductivity of aqueous polymer solutions 2. Effects of octaethylene glycol mono(n-dodecyl)ether upon the poly(acrylic acid) coil, Progr. Colloid Polym. Sci., 109 (1998) 136-141
8. V. Raicu, C. Gusbeth, D.F. Anghel and G. Turcu, effects of cetyltrimethylammonium bromide (CTAB) surfactant upon the dielectric properties of yeast cells, Biochim. Biophys. Acta: General Subjects, 1379 (1998) 7-15
7. V. Raicu, A. Baran, A. Iovescu, D.F. Anghel and S. Saito, Electrical conductivity of aqueous polymer solutions 1. Theory and experimental verification, Colloid Polym. Sci. 275 (1997) 372-377
6. M. Olteanu, S. Peretz, V. Raicu and O. Cinteza, Adsorption influence of some polymers upon aqueous graphite dispersions (in Romanian), Analele Univ. Bucuresti, 6 (1997) 73
5. V. Raicu, G. Raicu and G. Turcu, Dielectric properties of yeast cells as simulated by the two-shell model, Biochim. Biophys. Acta.: Bioenergetics, 1274 (1996) 143-148
4. D. Nita, V. Raicu and D.F. Anghel, Dielectric behavior of yeast cell membrane treated with anionic surfactants, Rom. J. Biophys., 6 (1996) 75-82
3. M. Olteanu, S. Peretz, V. Raicu, O. Cinteza and V.D. Branda, Concentrated graphite suspensions in aqueous polymer solutions, Trends. Coll. Polym. Sci., 100 (1996) 156-161
2. V. Raicu, A simple theoretical and practical approach to measuring dielectric properties with an open-ended coaxial line, Meas. Sci. Technol. 6 (1995) 410-414
1. V. Raicu, D.F. Anghel and G. Turcu, Heat-induced changes of the yeast plasma membranes, Rom. J. Biophys. 4 (1994) 95-100
Invited Talks
54. V. Raicu, FRET spectrometry of GPCRs: Probing receptor quaternary structure a few oligomers at a time, 21st Great Lakes GPCR Retreat, Niagara on the Lake, Ontario, May 13, 2022
53. V. Raicu, Distance- and diffusion-based methods for probing macromolecular association in living cells, Physics and Astronomy Colloquium, Wayne State University, Detroit, Online, November 12, 2021
52. V. Raicu, Fluorescence fluctuations- and energy transfer-based methods for probing protein oligomerization in living cells, Biophysical Society of Canada Annual Meeting, Online, May 28, 2021
51. V. Raicu, Förster Resonance Energy Transfer (FRET) and Fluorescence Intensity Fluctuation (FIF) spectrometries for probing macromolecular association in living cells, Romanian National Biophysics Conference, Online, June 13-14, 2020
50. V. Raicu, 2D Forster Resonance Energy Transfer (FRET) and Fluorescence Intensity Fluctuation (FIF) spectrometries, 5th Annual Symposium on Optical Microspectroscopy and Molecular Imaging, Milwaukee WI, August 2019
49. V. Raicu, FRET Spectrometry and its relatives: Application to receptor association studies, Molecular Biosciences Seminar, University of Kansas, November 19, 2018
48. V. Raicu, Fluorescence Micro-spectroscopy Techniques for Probing Protein Association in Living Cells, International Conference on Analytical and Nanoanalytical Methods for Biomedical and Environmental Sciences (IC-ANMBES), Brasov, Romania, May 2018
47. V. Raicu, Determining the quaternary structure of membrane receptors using fluorescence-based probes, Photonics North, Ottawa, Canada, June 2017
46. V. Raicu, Quaternary structure of proteins in living cells probed micro-spectroscopically: Towards multi-dimensional FRET spectrometry, 100th Canadian Chemistry Conference and Exhibition, May 28-June 1, 2017
45. V. Raicu, Probing Association and Dissociation of Proteins in Living Cells: Toward Multi-Dimensional FRET Spectrometry, International Conference on Analytical and Nanoanalytical Methods for Biomedical and Environmental Sciences (IC-ANMBES), Brasov, Romania, June 2016
44. V. Raicu, Quaternary structure of proteins in living cells probed with FRET spectrometry, 3rd Annual Symposium on Optical Microspectroscopy and Molecular Imaging, Milwaukee WI, August 2015
43. V. Raicu, Quaternary structure of proteins in living cells probed with FRET spectrometry, Biomaterials REU Program, Invited Speaker, Syracuse University, Syracuse NY, June 2015
42. V. Raicu, FRET Spectrometry: Application to Monitoring Protein Interactions and Quaternary Structure in Living Cells,International Conference on Analytical and Nanoanalytical Methods for Biomedical and Environmental Sciences (IC-ANMBES) Conference, Transilvania University of Brasov, Brasov, Romania, June 2014
41. V. Raicu, Micro-Spectroscopic Method for Determination of Quaternary Structure of Proteins in Living Cells, University of Bucharest, Bucharest, Romania, June 2014
40. V. Raicu, Quaternary Structure of GPCRs Probed with FRET Spectrometry, GPCR Structure, Function and Drug Discovery Conference, Cambridge MA, May 2014
39. V. Raicu, Optical Micro-Spectroscopy: Application to Determination of Protein Quaternary Structure in Living Cells, University of Delaware, Newark, DE, May 2013
38. V. Raicu, New Method for Studying Quaternary Structure of GPCR Proteins in vivo in Real Time, Webinar, Milwaukee WI, November 2012
37. V. Raicu, Quantitative Study of Protein Oligomerization in Living Cells, University of Arizona-Tucson, Tucson AZ, November 2012
36. V. Raicu, An Optical Micro-spectroscopic (OptiMiS) Approach to Determining Protein Quaternary Structure in Living Cells Using FRET, Northwestern University School of Medicine Cell Imaging Center, Chicago IL, November 2012
35. V. Raicu, Probing Protein Quaternary Structure in Living Cells Using Optical Micro-Spectroscopy (OptiMiS) and FRET, AiF Seminar, Albert Einstein College of Medicine Analytical Imaging Facility, New York, New York, October 2012
34. V. Raicu, Probing Stoichiometry and Quaternary Structure of Membrane Protein Complexes in Live Cells, Nano@Wayne,Wayne State University Division of Research, Detroit, MI, October, 2012
33. V. Raicu, Probing Protein Quaternary Structure in Living Cells Using Optical Micro-Spectroscopy (OptiMiS) and FRET, Center for Nanoscale Systems Seminar, Harvard University, Boston, MA, October 2012
32. V. Raicu, Optical Micro-Spectroscopy Instrumentation and its Application to the Determination of the Quaternary Structure and Distribution in Living Cells of GPCR Homo-Oligomers, Discovery on Target Conference, Boston, MA, October 2012
31. V. Raicu, Probing Protein Quaternary Structure in Living Cells Using Optical Micro-Spectroscopy (OptiMiS) and FRET,Biological Imaging Facility Seminar, Northwestern University Evanston, IL, October 2012
30. V. Raicu, Determination of the Quaternary Structure of Transporters and Receptors in Living Cells Using FRET and Optical Micro-Spectroscopy, W.M. Keck Laboratory for Biological Imaging Lecture Series, University of Wisconsin, Madison, WI, October 2012
29. V. Raicu, Detection of Protein Complex Stoichiometry and Geometry Using FRET-Based Imaging of Live Cells, FASEB Molecular Biophysics of Membranes Conference, Aspen, Co, June 2012
28. V. Raicu, Optical Micro-Spectroscopy: Application to Determination of the Quaternary structure of Membrane Transporters and Receptors in Living Cells Using FRET, Biophysics Seminar Series, University of Toronto-Mississauga, Mississauga, ON, Canada, June 2012
27. V. Raicu, FRET-Based Imaging of the Distribution and Supra-Molecular Association of Proteins in Living Cells, Live-Cell Imaging Conference, San Francisco California, January 2012
26. V. Raicu, Probing protein complex stoichiometry and geometry in live cells, Seminar, Max Planck Institute for Immuno-Biology, Freiburg, Germany, Sep 2011
25. V. Raicu, Probing protein quaternary structure in live cells, International Conference on Processes in Isotopes and Molecules, Cluj Napoca, Romania, Sep 2011
24. V. Raicu, A unitary approach to relaxation and dispersion in fractal networks: From dielectric and mechanical relaxation to distribution of income, NATO Advanced Workshop on Broadband Dielectric Spectroscopy and its Advanced Technological Applications, Perpignan, France, Sep 2011
23. V. Raicu, Comparative dielectric and optical microspectroscopic studies of the cellular response to signaling molecules,Department of Applied Physics Seminar, The Hebrew University of Jerusalem, Jerusalem, Israel, Mar 2011
22. V. Raicu, Determination of the stoichiometry and supramolecular structure of protein complexes in live cells, Materials Science Seminar, Johns Hopkins University, Baltimore, Maryland, Mar 2011
21. V. Raicu, Determination of stoichiometry, supramolecular structure, and distribution in living cells of proteins, Laboratory for Optical and Computational Instrumentation Workshop, University of Wisconsin-Madison, Madison, WI, Feb 2011
20. V. Raicu, Probing the stoichiometry and supramolecular structure of GPCR oligomers in living cells using fluorescence microspectroscopy and FRET, Great Lakes GPCR Retreat, Toronto, ON, Oct 2010
19. V. Raicu, Determination of the association stoichiometry and supramolecular structure of protein complexes in vivo, First International Congress on Analytical and Nanoanalytical Methods for Biomedical and Environmental Sciences, Brasov, Romania, Jun 18-22, 2010 (plenary)
18. V. Raicu, Tag-free detection of the internalization of the yeast a-factor pheromone in the absence and presence of its specific receptor in living cells, Biophysics Seminar, Physics Faculty, University of Bucharest, Bucharest, Romania, Jun 14, 2010
17. V. Raicu, In-vivo determination of the structure and distribution of protein complexes, Seminar, NSF Center for Biophotonics Science and Technology, UC Davis, CA, Apr 2010
16. V. Raicu, FRET-based determination in living cells of the stoichiometry and geometry of some GPCR homo-oligomers in the presence and absence of ligands, Drug Discovery Chemistry, San Diego, CA, Apr 2010
15. V. Raicu, Determination of protein complex structure in living cells using nonlinear optical microscopy and FRET, Southeast Asian International Advances in Nanotechnology, Chulalongkorn University, Bangkok, Thailand, Mar 09, 2010
14. V. Raicu, Resonance energy transfer: a method for detection of molecular interactions at nanometer length scale, Southeast Asian International Advances in Nanotechnology, Chulalongkorn University, Bangkok, Thailand, Mar 08, 2010
13. V. Raicu, Determination of structure and distribution of protein complexes in living cells, Condensed Matter & Biological Physics Seminar, Syracuse University, Department of Physics, Syracuse, New York, USA, Nov 13, 2009
12. V. Raicu, In-vivo determination of structure and distribution of oligomers of membrane receptors, Physics of Living Systems Seminar, University of Illinois at Urbana-Champaign, Physics Department, Urbana, Illinois, USA, October 2009
11. V. Raicu, FRET-Based Determination of Structure and Distribution of Protein Complexes in Living Cells, High-Content Analysis East, Live-Cell Imaging, Boston, MA, USA, Sep 2009
10. V. Raicu, Biological systems, imaging techniques, 6th International Discussion Meeting on Relaxations in Complex Systems,Tutorial on Novel Applications of Broadband Dielectric Spectroscopy, Rome, Italy, Aug 30 – Sep 5, 2009
9. V. Raicu, In vivo determination of structure and distributions of supra-molecular associations, European Biophysics Congress, Genoa, Italy, Jul 2009
8. V. Raicu, FRET-based determination of structure and distribution of protein complexes in vivo, University of Wisconsin-Madison,Biomedical Engineering Seminar Series, Madison, Wisconsin, Apr 27, 2009
7. V. Raicu, Use of multiphoton excitation microscopy in FRET-based imaging of protein-protein interactions in vivo, Marquette University, Department of Biological Sciences, Milwaukee, Wisconsin, Sep 2007
6. V. Raicu, Developing photonic tools for studies of protein-protein interactions in living cells, University of Bucharest, Faculty of Physics, Bucharest, Romania, Jun 2007
5. V. Raicu, Universal patterns in the behavior of complex systems: From relaxation of macromolecules to distribution of income in human populations, University of Toronto at Mississauga, Department of Physical and Chemical Sciences Colloquium, Mississauga, Ontario, Canada, Nov 2006
4. V. Raicu, Spectroscopic studies of biological tissues, cells, and macromolecules: Toward hyperspectral imaging of the proteome inside the living cell, Department of Physics, University of Lethbridge, Alberta, Canada, Jan 2004
3. V. Raicu, Quantification of protein distribution and interaction in living cells, University of Toronto at Mississauga, Department of Physical and Chemical Sciences Seminar, Mississauga, Ontario, Canada, Jul 2004
2.V. Raicu, Electrical signatures of the biological cells revealed by dielectric (impedance) spectroscopy: implications for the study of drug interaction with plasma membrane, MDS SCIEX INC Lecture, Toronto, Canada, Jun 2003
1. V. Raicu, Electrical properties of systems of micrometer/nanometer-size particles with particular emphasis on aggregation and structuring effects, Institute of Physical Chemistry of the Romanian Academy, Bucharest, Romania, Aug 2000
Conference Presentations
46. J.D. Paprocki, M.R. Stoneman, G. Biener, K. Yokoi, J.C. Cruz, A. Shevade, K. Hristova, S. Kuchin, V. Raicu, Surprising membrane penetration by the yeast α-factor pheromone regulates cognate receptor quaternary structure in the cell, 100th Canadian Chemistry Conference and Exhibition, May 28-June 1, 2017
45. K. Yokoi, V. Raicu, Theoretical studies of molecular structure using FRET and molecular dynamic simulations, Federation of American Societies for Experimental Biology (FASEB) – Molecular Biophysics of Membranes Conference, Big Sky, Montana, USA, June 2014
44. M. Stoneman, J. Paprocki, G. Biener, V. Raicu, Monitoring G protein coupled receptor interactions using a spectrally resolved fluorescence microscope with line scan excitation, Federation of American Societies for Experimental Biology (FASEB) – Molecular Biophysics of Membranes Conference, Big Sky, Montana, USA, June 2014
43. S. Patowary, E. Alvarez-Curto, T.R. Xu, J.D. Holz, J. Oliver, G. Milligan, V. Raicu Probing the stoichiometry and geometry of M3 acetylcholine receptors at the plasma membrane, Biophysical Society Annual Meeting, Philadelphia, PA USA, Feb 2013
42. A.K. Mishra, D.R. Singh, T.G. Kim, J. Oliver, P. Park, V. Raicu, Determination of quaternary structure of rhodopsin at room and body temperature using spectral FRET, Biophysical Society Annual Meeting, Philadelphia, PA USA, Feb 2013
41. S. Patowary, E. Alvarez-Curto, T.R. Xu, J.D. Holz, J. Oliver, G. Milligan, V. Raicu Quaternary structure determination of the M3 muscarinic acetycholine receptors based on spectral-FRET Biophysical Society Annual Meeting, San Diego, CA USA, Feb 2012
40. D.R. Singh, M.M. Mohammad, K. Howard, J. Oliver, L. Movileanu, V. Raicu, Quaternary structure of the NBD subunit WZT of a bacterial ABC transporter in the absence and presence of the TMD subunit WZM using pixel-level FRET, Biophysical Society Annual Meeting, San Diego, CA USA, Feb 2012
39. S. Patowary, L.F. Pisterzi, M.R. Stoneman, V. Strogolov,J. A. Oliver, J. W. Wells, V. Raicu, Experimental testing of the FRET theory for multimeric complexes using reference fluorescence standards, FRET at 65-One Day Symposium, University of Virginia, Charlottesville, VA, Mar 2011
38. D.R. Singh, M.M. Mohammad, K.R. Howard, J.A. Oliver, L. Movileanu, and V. Raicu, Localization, interaction and stoichiometry of the wzm and wzt subunits of a bacterial ABC transporter using spectrally resolved FRET, FRET at 65-One Day Symposium, University of Virginia, Charlottesville, VA, USA, Mar 2011
37. M.R. Stoneman, S. Patowary, M.T. Roesch, M. Dey, and V. Raicu, In Vivo Monitoring of Agonist-Induced Relative Movements Between G Protein Coupled Receptor Segments in Oligomeric Complexes Using Spectrally Resolved FRET, Biophysical Society Annual Meeting, Baltimore, MD, USA, Mar 2011
36. S. Patowary, L.F. Pisterzi, M.R. Stoneman, V. Strogolov, J.A. Oliver, J. W. Wells,V. Raicu, Accurate FRET measurements and testing of the theory for multimeric complexes using reference fluorescence standards, Biophysical Society Annual Meeting, Baltimore, Maryland, Mar 2011
35. M.R. Stoneman, D.R. Singh and V. Raicu, Determination of stoichiometry and geometry of G protein coupled receptor homo-oligomers in living cells using spectrally resolved FRET, Biophysical Society Annual Meeting, San Francisco, CA, USA, Mar 2010
34. D.R. Singh, K. Michalski and V. Raicu, Information Extraction From Simulations-Based Data Fitting of Distributions of Fret Efficiencies from Donors and Acceptors in the Cytoplasm of Living Cells, Biophysical Society Annual Meeting, San Francisco, CA, USA, Mar 2010
33. L.F. Pisterzi, M.R. Stoneman, F. Huang, J.W. Wells and V. Raicu, Oligomeric size and configuration of the M2 muscarinic and β2 adrenergic receptors in live cells as determined by pixel-level FRET, Biophysical Society Annual Meeting, San Francisco, CA, USA, Mar 2010
32. M.R. Stoneman, D.R. Singh and V. Raicu, In vivo stoichiometry monitoring of G protein coupled receptor oligomers using spectrally resolved two-photon microscopy, Photonics West, San Francisco, CA, USA, Feb 2010 (oral)
31. M. Habibi, D.P. Klemer, V. Raicu, Implementation of a fast reconfigurable array for tissue impedance characterization, 31st Annual International Conference of the IEEE EMBS, Minneapolis, MN, USA, Sep 2-6, 2009 (oral)
30. L.F. Pisterzi, D.B. Jansma, J. Georgiou, M. J. Woodside, J. Tai-Chieh Chou, S. Angers, V. Raicu, Oligomeric size of the M2muscarinic receptor in the plasma membrane of live cells as determined by quantitative FRET, Biophysical Society Annual Meeting, Boston, MA, USA, 875-Pos, Feb 28 – Mar 4, 2009
29. L.F. Pisterzi, M.R. Stoneman, J.W. Wells, V. Raicu, Oligomeric Size of the M2 Muscarinic receptor in live cells as determined from FRET efficiencies at the level of single pixels, Biophysical Society Annual Meeting, Boston, MA, USA, 876-Pos, Feb 28 – Mar 4, 2009
28. V. Raicu, Microspectroscopic method for determination of size and distribution of protein complexes in vivo, SPIE Scanning Microscopy, Monterey, CA, USA, May 4-7, 2009 (oral)
27. L.F. Pisterzi, D.B. Jansma, J. Georgiou, J.T-C Chou, S Angers, V. Raicu, J.W. Wells, Relationship between FRET efficiency and oligomeric size for M2 muscarinic receptors in live cells, Biophysical Society Annual Meeting, Long Beach, CA, #1420-Pos, Feb 02-07, 2008
26. V. Raicu, Non-Debye dielectric behaviour and near-field interactions in biological tissues: when structure meets function, 5thInternational Conference on Broad-band Dielectric Spectroscopy, Lyon, France, Aug 2008 (oral)
25. V. Raicu, Application of a two-photon microscope with spectral resolution to correction-free determinations of FRET efficiency in living cells, 1st International Congress on Biophotonics, Sacramento, CA, USA, #R9, Feb 03-07, 2008
24. V. Raicu, M.R. Stoneman and R. Fung, Universal patterns in the behavior of complex systems: from relaxation in fractal networks to distribution of income, American Physical Society March Meeting, Denver, CO, USA, #D35.00011, Mar 05-09, 2007 (oral)
23. R. Fung, M. Melnichuk, A. Chaturvedi, D. Gillman, V. Raicu, Two-Photon Microscope with Spectral Resolution, American Physical Society March Meeting, Denver, CO, USA, #B38.00004, Mar 05-09, 2007 (oral)
22. M. Stoneman, A. Chaturvedi, D.B. Jansma, M. Kosempa, C. Zeng, V. Raicu, Protein influence on the plasma membrane dielectric properties: towards tag-free detection of proteins, Chemical Biophysics Symposium, Toronto, Canada, #Vd, Apr 20-22, 2007 (oral)
21. V. Raicu, D.B. Jansma, J.D. Friesen, K. Michalski, Fluorescence Resonance Energy Transfer-based stoichiometry of molecular interactions: harnessing “inadvertent” donor photobleaching, Biophysical Society Annual Meeting, Salt Lake City, USA, #683-Pos, Feb 17-22, 2006
20. M.R. Stoneman, D.B. Jansma, K. Michalski, C. Zeng, V. Raicu, Tag-Free detection of yeast cell membrane receptors by using dielectric spectroscopy: a feasibility study, Biophysical Society Annual Meeting, Salt Lake City, USA, #2391-Pos, Feb 17-22, 2006
19. V. Raicu, D.B. Jansma, J.D. Friesen, Fluorescence Resonance Energy Transfer – a test-bench for fundamental laws of naturein vivo, Chemical Biophysics Symposium, Toronto, Canada, #Ic, Apr 08-10, 2005 (oral)
18. R. Fung, V. Raicu, D.K. Saldin, D.B. Jansma, J. D. Friesen, Protein interaction quantification by spatially and spectrally resolved fluorescence resonance energy transfer, Chemical Biophysics Symposium, Toronto, Canada, #P28, Apr 08-10, 2005
17. V. Raicu, D.B. Jansma, J.D. Friesen, R.J.D. Miller, Studying chemistry inside the living cell: proteins and their interactions,Chemical Biophysics Symposium, Toronto, Canada, #VIb, Mar 19-21, 2004 (oral)
16. M. Walther, V. Raicu, R.J.D. Miller, B.M. Fischer, H. Helm, P.U. Jepsen, Photodissociation of carboxymyoglobin studied by four-wave mixing techniques and THz-spectroscopy, Annual Meeting of Deutsche Physikalische Gesellschaft, Physical Chemistry and Polymer Physics Symposium, Dresden, Germany, # CPP 21.6, Mar 24-28, 2003 (oral)
15. V. Raicu, A. Irimajiri, T. Saibara, T. Yamashiro, T. Mima, A.K. Jonscher, Dielectric dispersion of biological tissues – revisited,World Congress on Medical Physics and Biomedical Engineering, Chicago, Jul 23-28, 2000
14. V. Raicu, C. Gusbeth, D. Niţă, G. Turcu, Investigation of the surfactant-treated biological membranes by dielectric spectroscopy, VIII-th Conference of Physical Chemistry, Bucharest, Romania, Sep 25-27, 1996 (oral)
13. M. Balcan, D.F. Anghel, D. Donescu, V. Raicu, N. Galaţanu, The hydrophile-lypophile properties of nonionic surfactants as investigated by RP-HPLC”, VIII-th Conference of Physical Chemistry, Bucharest, Romania, Sep 25-27, 1996 (oral)
12. D. Niţă, V. Raicu, C. Gusbeth, D.F. Anghel, Interaction of cationic surfactants with biological membranes. Theoretical and experimental approach, VIII-th Conference of Physical Chemistry, Bucharest, Romania, Sep 25-27, 1996 (Oral)
11. M. Olteanu, S. Peretz, V. Raicu, O. Cinteza, V.D. Branda, Concentrated graphite suspensions in aqueous polymer solutions,IX-th Conference of European Colloid and Interface Society, Barcelona, Spain, Sep 17-22, 1995
10. M. Olteanu, S. Peretz, V. Raicu, and O. Cinteza, Adsorption influence of some polymers upon aqueous graphite dispersions,V-th Symposium of Colloid and Surface Chemistry, Timisoara, Romania, Sep 25-27, 1995
9. D. Niţă, V. Raicu, D.F. Anghel, Interaction of sodium dodecyl sulfonate with cellular membrane as investigated by dielectric spectroscopy, V-th Symposium of Colloid and Surface Chemistry, Timisoara, Romania, Sep 25-27, 1995
8. V. Raicu, D. Nita, D.F. Anghel, G. Turcu, C. Bobica, Can cationic surfactants change the conductance of biological cell membrane? Annual Conference of the Romanian Society of Pure and Applied Biophysics, Bucharest, Romania, Oct 1994
7. V. Raicu, D. Niţă, D.F. Anghel, C. Bobica, G. Turcu, The effect of anionic surfactants upon biological cells as studied by dielectric spectroscopy and optical absorption measurements, VIII-th European Colloid & Interface Society Conference, Montpellier, France, Sep 26-30, 1994
6. M. Olteanu, S. Peretz, V. Raicu, O. Cinteza, Conductivity dispersions of concentrated polymer stabilized graphite suspensions,VIII-th European Colloid and Interface Society Conference, Montpellier, France, Sep 26-30, 1994
5. M. Olteanu, O. Cinteza, S. Peretz, V. Raicu, Physico-chemical characteristics of some concentrated graphite suspensions, VII-th Conference of Physical Chemistry, Bucharest, Romania, Sep 21-23, 1994
4. D. Niţă, V. Raicu, D.F. Anghel, C. Bobica, Interaction of ionic surfactants with biological membranes, VII-th Conference of Physical Chemistry, Bucharest, Romania, Sep 21-23, 1994 (Oral)
3. V. Raicu, C. Bobica, D. Niţă, D.F. Anghel, S. Peretz, and G. Turcu, Interaction of hexadecyltrimethylammonium bromide with charged yeast plasma membranes, ESF Conference on Supramolecular Chemistry, Molecular Recognition from Biology to Materials, Mainz, Germany, Aug 11-16, 1994
2. V. Raicu, D.F. Anghel, G. Turcu, Structural modifications of the biological membranes by heating, European Science Foundation Conference on Interfaces and Colloidal Systems, York, UK, Sep 03-08, 1993
1. V. Raicu, G. Turcu, Study of membrane permeability by means of dielectric spectroscopy, International Summer School on Proton and Ion Transport. Satellite Meeting of the 11-th International Biophysics Congress, Brasov, Romania, Jul 31-Aug 06 1993