Insights into periplasmic nitrate reductase function under single turnover
Jennifer McGarry, Breeanna Mintmier, Mikayla C Metzger, Nitai C. Giri, Nicholas Britt, Partha Basu* & Jarett Wilcoxen*
J Biol Inorg Chem., 2024, 29, 811-819.
Active Site Characterization of a Campylobacter jejuni Nitrate Reductase Variant Provides Insight into the Enzyme Mechanism
Jing Yang, Breeanna Mintmier, Khadanand Kc, Mikayla C Metzger, Manohar Radhakrishnan, Jennifer McGarry, Jarett Wilcoxen*, Partha Basu*, Martin L Kirk*
Inorg. Chem., 2024, 63, 13191–13196.
The critical role of a conserved lysine residue in periplasmic nitrate reductase catalyzed reactions
Nitai C. Giri, Breeanna Mintmier, Manohar Radhakrishnan, Jonathan W. Mielke, Jarett Wilcoxen*, & Partha Basu*
J Biol Inorg Chem., 2024, 29, 395–405 (2024).
Tracing the incorporation of the “ninth sulfur” into the nitrogenase cofactor precursor with selenite and tellurite
Tanifuji, K., Jasniewski, A.J., Villarreal, D., Stiebritz, M.T., Lee, C.C., Wilcoxen, J., Okhi, Y., Chatterjee, R., Bogacz, I., Junko Yano, J., Kern, J., Hedman, B., Hodgson, K.O., Britt, R.D.*, Hu, Y.*, and Ribbe, M.W.*
Nature Chemistry, 2021
A Kinetic Investigation of the Early Steps in Cytochrome c Nitrite Reductase (ccNiR)-Catalyzed Reduction of Nitrite.
Shahid, S., Ali, M., Legaspi-Humiston, D., Wilcoxen, J., and Pacheco, A.A.*.
Biochemistry, 2021, 60, 2098-2115
Identity and function of an essential nitrogen ligand of the nitrogenase cofactor biosynthesis protein NifB.
Rettenberg, L.A., Wilcoxen, J., Jasniewski, A.J., Lee, C.C., Tanifuji, K., Hu, Y.*, Britt, R.D.*, and Ribbe, M.*
Nature Communications 2020 11, Article number: 1757
Isolation and Study of Ruthenium–Cobalt Oxo Cubanes Bearing a High-Valent, Terminal RuV–Oxo with Significant Oxyl Radical Character.
Amtawong, J., Balcells, D., Wilcoxen, J., Handford, R.C., Biggins, N., Nguyen, A.I., Britt, R.D.*, Tilley, T.D.*
J. Am. Chem. Soc. 2019 141, 19859-19869
Spectroscopic Characterization of an Eight‐Iron Nitrogenase Cofactor Precursor That Lacks the “9th Sulfur”.
Jasniewski, A.J., Wilcoxen, J., Tanifuji, K., Hedman, B., Hodgson, K.O., Britt, R.D.*, Hu, Y.*, Ribbe M.W.*
Angew. Chem. 2019
Biophysical Characterization of a Disabled Double Mutant of Soybean Lipoxygenase: The “Undoing” of Precise Substrate Positioning Relative to Metal Cofactor and an Identified Dynamical Network
Hu, S., Offenbacher, A., Thompson, E., Gee, C., Wilcoxen, J., Carr, C., Prigozhin, D., Yang, V., Alber, T., Britt, R.D.*, Fraser, J.*, Klinman, J.*
J. Am. Chem. Soc. 2019, 141, 1555-1567
Probing the Coordination and Function of Fe4S4 Modules in Nitrogenase Assembly Protein NifB
Rettberg, L.A.+, Wilcoxen, J.+, Lee, C.C., Stiebritz, M.T., Tanifuji, K., Britt, R.D.*, and Hu, Y.*
Nature Communications 2018 9, 2824
A Radical Intermediate is Identified in QueE from Bacillus subtilis using 6-Carboxypterin as an Alternative Substrate.
Wilcoxen, J., Bruender, N.A., Bandarian, V., Britt, R.D.*
J. Am. Chem. Soc. 2018, 140, 1753–1759
Evaluation of the Catalytic Relevance of the CO-bound States of V-Nitrogenase
Lee, C.C., Wilcoxen, J., Hiller, C.J., Britt, R.D.* and Hu, Y.*
Angew. Chem. Int. Ed. 2018, 57, 3411–3414
Protonation of the Hydroperoxo Intermediate of Cytochrome P450 2B4 is Slower in the Presence of Cytochrome P450 Reductase than in the Presence of Cytochrome b5.
Pearl, N.M., Wilcoxen, J., Im, S., Kunz, R., Darty, J., Britt, R.D.*, Ragsdale, S.W.*, Waskell, L.*
Biochemistry, 2016, 55, 6558–6567
Studies of Carbon Monoxide Dehydrogenase from Oligotropha carboxidovorans.
Dingwall, S., Wilcoxen, J., Niks, D., Hille, R.*
Journal of Molecular Catalysis B: Enzymatic. 2016, 134, 317-322
Electron Paramagnetic Resonance Characterization of Three Iron–Sulfur Clusters Present in the Nitrogenase Cofactor Maturase NifB from Methanocaldococcus infernus.
Wilcoxen, J.+, Arragain, S.+, Scandurra, A.A., Jimenez-Vicente, E., Echavarri-Erasun, C., Pollmann, S., Britt, R.D.*, and Rubio, L.M.*
J. Am. Chem. Soc. 2016, 138, 7468-7471
Biochemical and Spectroscopic Characterization of a Radical SAM Enzyme Involved in the Formation of a Peptide Thioether Crosslink.
Bruender, N.A., Wilcoxen, J., Britt, R.D.*, and Bandarian, V.*
Biochemistry. 2016, 55, 2122-2134
Formation of Hexacoordinate Mn(III) in Bacillus subtilis Oxalate Decarboxylase Requires Catalytic Turnover.
Zhu, W.+, Wilcoxen, J.+, Britt, R.D.*, and Richards, N.G.J.*
Biochemistry. 2016, 55, 429-434
The Aerobic CO Dehydrogenase from Oligotropha carboxidovorans.
Hille, R.*, Dingwall, S., Wilcoxen, J.
J. Bio. Inorg. Chem. 2015 20, 243-251
13C and 63,65Cu ENDOR studies of CO dehydrogenase from Oligotropha carboxidovorans Experimental Evidence in Support of a Copper-Carbonyl Intermediate.
Shanmugam, M., Wilcoxen, J., Habel-Rodriguez, D., Cutsail III, G. E., Kirk, M., Hoffman, B.*, and Hille, R.*
J. Am. Chem. Soc. 2013, 135, 17775
Kinetic and Spectroscopic Studies of H2 Oxidation by the Mo/Cu containing Carbon Monoxide Dehydrogenase of Oligotropha carboxidovorans.
Wilcoxen, J. and Hille, R.*
J. Biol. Chem. 2013, 288, 36052-36060
CO Dehydrogenase from Oligotropha carboxidovorans.
Hille, R.*, Wilcoxen, J., Zhang, B., and Snider, S.
Flavins and Flavoproteins 2011; 1 ed., Lulu, Raleigh, NC, 2013 ISBN-13: 978-1300786405
The Reaction of the Molybdenum- and Copper- Containing Carbon Monoxide Dehydrogenase from Oligotropha carboxydovorans with Quinones.
Wilcoxen, J.;Zhang, B.; Hille, R.*
Flavins and Flavoproteins 2011; 1 ed.; Lulu: Raleigh, NC, 2013 ISBN-13: 978-1300786405
Substitution of Silver for Copper in the Binuclear Mo/Cu Center of Carbon Monoxide Dehydrogenase from Oligotropha carboxidovorans
Wilcoxen, J., Snider, S., and Hille, R.*
J. Am. Chem. Soc. 2011 133, 12934-12936
Reaction of the Molybdenum- and Copper-Containing Carbon Monoxide Dehydrogenase from Oligotropha carboxydovorans with Quinones.
Wilcoxen J., Zhang, B., and Hille, R.*
Biochemistry. 2011 50, 1910–1916
* = Corresponding Author
+ = Co-first Author